Inflammation, infection and venous thromboembolism

ME Colling, BE Tourdot, Y Kanthi - Circulation research, 2021 - Am Heart Assoc
The association between inflammation, infection, and venous thrombosis has long been
recognized; yet, only in the last decades have we begun to understand the mechanisms …

Pitfalls in complement analysis: A systematic literature review of assessing complement activation

RJ Brandwijk, MAHM Michels, M van Rossum… - Frontiers in …, 2022 - frontiersin.org
Background The complement system is an essential component of our innate defense and
plays a vital role in the pathogenesis of many diseases. Assessment of complement …

Vaccine-induced COVID-19 mimicry syndrome

E Kowarz, L Krutzke, M Külp, P Streb, P Larghero… - Elife, 2022 - elifesciences.org
To fight the Covid-19 pandemic caused by the RNA virus SARS-CoV-2 a global vaccination
campaign is in progress to achieve the immunization of billions of people mainly with …

Status of mannose-binding lectin (MBL) and complement system in COVID-19 patients and therapeutic applications of antiviral plant MBLs

A Gupta, GS Gupta - Molecular and Cellular Biochemistry, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is an infectious disease caused by a virus
called “Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).” In the majority of …

Influence of nanoparticles on the haemostatic balance: between thrombosis and haemorrhage

HDN Tran, SS Moonshi, ZP Xu, HT Ta - Biomaterials Science, 2022 - pubs.rsc.org
Maintenance of a delicate haemostatic balance or a balance between clotting and bleeding
is critical to human health. Irrespective of administration route, nanoparticles can reach the …

[HTML][HTML] How NETosis could drive “Post-COVID-19 syndrome” among survivors

SA Sawadogo, B Dighero-Kemp… - Immunology …, 2020 - ncbi.nlm.nih.gov
The extensive world propagation of SARS-CoV-2 with millions of cases of COVID-19 and its
high severity and mortality rates is an unprecedented situation. Initially focused on the …

The complement system in kidney transplantation

D Santarsiero, S Aiello - Cells, 2023 - mdpi.com
Kidney transplantation is the therapy of choice for patients who suffer from end-stage renal
diseases. Despite improvements in surgical techniques and immunosuppressive treatments …

Immune thrombocytopenic purpura as a hemorrhagic versus thrombotic disease: an updated insight into pathophysiological mechanisms

CC Tărniceriu, LL Hurjui, ID Florea, I Hurjui, I Gradinaru… - Medicina, 2022 - mdpi.com
Immune thrombocytopenic purpura (ITP) is a blood disorder characterized by a low platelet
count of (less than 100× 109/L). ITP is an organ-specific autoimmune disease in which the …

[HTML][HTML] Complement and coagulation crosstalk–Factor H in the spotlight

M Heurich, G McCluskey - Immunobiology, 2023 - Elsevier
The immune complement and the coagulation systems are blood-based proteolytic
cascades that are activated by pathway-specific triggers, based on protein–protein …

Efficacy and mechanism of buyang huanwu decoction in patients with ischemic heart failure: a randomized, double-blind, placebo-controlled trial combined with …

M Zhu, J Wei, Y Li, Y Wang, J Ren, B Li, B Ma… - Frontiers in …, 2022 - frontiersin.org
Objective: Buyang Huanwu Decoction (BYHW), a famous herbal prescription in traditional
Chinese medicine (TCM), has been used for 200 years for treating ischemic heart failure …