Research studies that focus on understanding the onset of neurodegenerative pathology
and therapeutic interventions to inhibit its causative factors, have shown a crucial role of …

The 5xFAD mouse model of Alzheimer's disease (AD) rapidly develops AD‐related neuro‐
behavioral pathology. Learning and memory impairments in 5xFAD mice, however, are not …

Olfactory dysfunction is considered a pre-cognitive biomarker of Alzheimer's disease (AD).
Because the olfactory system is highly conserved across species, mouse models …

Alzheimer's disease (AD) is the most common form of dementia. Although previous studies
have selectively investigated the localization of amyloid-beta (Aβ) deposition in certain brain …

Most patients with Alzheimer's disease (AD) develop neuropsychiatric symptoms (NPS)
alongside cognitive decline, and apathy is one of the most common symptoms. Few …

Alzheimer's disease (AD) patients show age-related decreases in the ability to perform
activities of daily living and the decline in these activities is related to the severity of …

The acquisition of complex rules requires modifications in intrinsic plasticity of excitatory
neurons within relevant brain areas. Olfactory discrimination (OD) rule learning occludes …

Simple Summary We observed that compared to wildtype (WT) littermates, 5× FAD mice
showed enhanced anxiety with concomitant increased pro-inflammatory cytokines in the …

One of the major challenges in treating Alzheimer's disease (AD) is its early diagnosis.
Increasing data from clinical and animal research indicate that the retina may facilitate an …

Alzheimer's disease (AD) is a severe neurodegenerative disorder and the most common
form of dementia in elderly individuals, characterized by memory deficits, cognitive decline …