Pertussis: microbiology, disease, treatment, and prevention

PE Kilgore, AM Salim, MJ Zervos… - Clinical microbiology …, 2016 - Am Soc Microbiol
Pertussis is a severe respiratory infection caused by Bordetella pertussis, and in 2008,
pertussis was associated with an estimated 16 million cases and 195,000 deaths globally …

Recent developments in pertussis

NS Crowcroft, RG Pebody - The Lancet, 2006 - thelancet.com
Pertussis causes nearly 300 000 deaths in children every year. Most deaths take place in
developing countries, but the infection remains a priority everywhere. Pertussis vaccination …

[图书][B] Kumar and Clark's clinical medicine E-Book

P Kumar, ML Clark - 2012 - books.google.com
Kumar & Clark's Clinical Medicine 8 builds on the prize-winning formula that won the first
prize in the BMA Book Awards Medicine Category in 2010 (7th edition) and 2006 (6th …

[图书][B] Bailey & Scott's diagnostic microbiology-E-Book

P Tille - 2015 - books.google.com
Perfect your lab skills with the gold standard in microbiology! Serving as both the# 1 bench
reference for practicing microbiologists and as a favorite text for students in clinical …

A fully integrated microfluidic genetic analysis system with sample-in–answer-out capability

CJ Easley, JM Karlinsey… - Proceedings of the …, 2006 - National Acad Sciences
We describe a microfluidic genetic analysis system that represents a previously undescribed
integrated microfluidic device capable of accepting whole blood as a crude biological …

Immunogenicity and safety of BPZE1, an intranasal live attenuated pertussis vaccine, versus tetanus–diphtheria–acellular pertussis vaccine: a randomised, double …

C Keech, VE Miller, B Rizzardi, C Hoyle, MJ Pryor… - The Lancet, 2023 - thelancet.com
Background Bordetella pertussis epidemics persist as transmission remains unabated
despite high acellular pertussis vaccination rates. BPZE1, a live attenuated intranasal …

Vaccine herd effect

TH Kim, J Johnstone, M Loeb - Scandinavian journal of infectious …, 2011 - Taylor & Francis
Vaccination ideally protects susceptible populations at high risk for complications of the
infection. However, vaccines for these subgroups do not always provide sufficient …

What is wrong with pertussis vaccine immunity? The problem of waning effectiveness of pertussis vaccines

N Burdin, LK Handy, SA Plotkin - Cold Spring Harbor …, 2017 - cshperspectives.cshlp.org
Pertussis is resurgent in some countries, particularly those in which children receive
acellular pertussis (aP) vaccines in early infancy and boosters later in life. Immunologic …

Prevalence and Genetic Characterization of Pertactin-Deficient Bordetella pertussis in Japan

N Otsuka, HJ Han, H Toyoizumi-Ajisaka, Y Nakamura… - PloS one, 2012 - journals.plos.org
The adhesin pertactin (Prn) is one of the major virulence factors of Bordetella pertussis, the
etiological agent of whooping cough. However, a significant prevalence of Prn-deficient …

Seroprevalence studies of pertussis: what have we learned from different immunized populations

AM Barkoff, K Gröndahl-Yli-Hannuksela… - Pathogens and …, 2015 - academic.oup.com
Bordetella pertussis is a pathogen-causing whooping cough (pertussis) in humans.
Although vaccination against the disease is effective, the bacterium is still circulating among …