As an essential micronutrient, copper is required for a wide range of physiological processes
in virtually all cell types. Because the accumulation of intracellular copper can induce …

Over 30 million people suffer from the consequences of ischemic stroke. The precise
molecular mechanism of neuronal damage during ischemic stroke remains unclear; …

Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by central nervous
(CNS) demyelination resulting in axonal injury and neurological deficits. Essentially, MS is …

Multiple sclerosis (MS) is an autoimmune, inflammatory demyelinating disorder of the central
nervous system. Accumulating evidence has underscored the therapeutic potential of bone …

Multiple sclerosis (MS) is a chronic inflammatory disease, which leads to focal demyelination
in the brain and spinal cord. Studies showed that iron released during the course of myelin …

Ferroptosis is a programmed cell death pathway that is recently linked to Parkinson's
disease (PD), where the key genes and molecules involved are still yet to be defined. Acyl …

Ferroptosis is defined as an iron-dependent regulated form of cell death driven by lipid
peroxidation. In the past decade, it has been implicated in the pathogenesis of various …

Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …

Multiple sclerosis is a severe demyelinating disease mediated by cells of the innate and
adaptive immune system, especially pathogenic T lymphocytes that produce the pro …

Ferroptosis is implicated in a range of brain disorders, but it is unknown whether neurons or
glia in the brain are particularly effected. Here, we report that primary astrocytes (PA) …