Insulin injection is currently the main therapy for type 1 diabetes (T1D) or late stage of
severe type 2 diabetes (T2D). Human pancreatic islet transplantation confers a significant …

Widespread provision of human embryonic stem cells (hESCs) for therapeutic use, drug
screening and disease modelling will require cell lines sustainable over long periods in …

Human embryonic stem (hES) cell lines are of great potential in cell transplantation therapy.
However, recipients of such allogeneic transplants probably need treatment with …

Congenital heart disease occurs in 1% of liveborn infants, making it the most common birth
defect worldwide. Many of these children develop heart failure. In addition, both genetic and …

Abstract Purpose of the Review Type 1 diabetes (T1D) is defined by an autoimmune
destruction of insulin producing β-cells located in the endocrine part of the pancreas, the …

The retina is a very fine and layered neural tissue, which vitally depends on the preservation
of cells, structure, connectivity and vasculature to maintain vision. There is an urgent need to …

Cardiac muscle restitution, or true regeneration, is an unmet need in the treatment of
myocardial infarction (MI), prompting a decade of study with stem cells of many kinds …

Individual HLA homozygous parthenogenetic human stem cell (hpSC-Hhom) lines have the
potential for cell-based therapy in a significant number of individuals, provided the HLA …

Great hopes have been placed on human pluripotent stem (hPS) cells for therapy. Tissues
or organs derived from hPS cells could be the best solution to cure many different human …

Developing safe therapies from human pluripotent stem cells | Nature Biotechnology Skip to
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