Liver resection causes marked perfusion alterations in the liver remnant both on the organ
scale (vascular anatomy) and on the microscale (sinusoidal blood flow on tissue level) …

Abstract Background Neutrophil extracellular traps (NETs) play a crucial role in host
defense, but excess and prolonged interaction of NETs with platelets can cause severe …

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and one of the
leading causes of cancer-related death. Cilostazol, an antiplatelet drug, elicits anticancer …

Alcoholic liver disease (ALD) is a worldwide health problem and hepatocyte apoptosis has
been associated with the development/progression of ALD. However, no definite effective …

Abstract Background and Aim Safe radical hepatectomy is important for patients with
colorectal liver metastases complicated by sinusoidal obstruction syndrome (SOS) after …

Background Cilostazol is a type III phosphodiesterase inhibitor used to treat the symptoms of
intermittent claudication. Recent studies have shown that cilostazol decreases …

正常肝再生能力强大, 而肝硬化肝再生能力低下, 肝功能储备不足, 致使肝切除术后肝衰竭发生率
大大增加, 限制了大范围肝切除术的开展. 肝硬化肝细胞虽具有再生能力, 但受到抑制 …

Cilostazol undergoes extensive liver metabolism. However, the transporter-mediated
hepatic disposition of cilostazol remains unknown. The present study was performed to …

Liver regeneration is an exceptionally complex process, orchestrated by a multitude of
growth factors and cytokines. Tumor necrosis factor-alpha (TNF-a) and interleukin-6 (Il-6) …

Background: Smokers are known to have a higher risk of erectile dysfunction. We examined
how daily consumption of low-dose tadalafil affected erectile function and circulation in …