Emerging evidence that the mammalian sperm epigenome serves as a template for embryo development

A Lismer, S Kimmins - Nature communications, 2023 - nature.com
Although more studies are demonstrating that a father's environment can influence child
health and disease, the molecular mechanisms underlying non-genetic inheritance remain …

Ferroptosis induced by pollutants: an emerging mechanism in environmental toxicology

L Yang, X Cai, R Li - Environmental Science & Technology, 2024 - ACS Publications
Environmental pollutants have been recognized for their ability to induce various adverse
outcomes in both the environment and human health, including inflammation, apoptosis …

Genetics of chronic respiratory disease

I Sayers, C John, J Chen, IP Hall - Nature Reviews Genetics, 2024 - nature.com
Chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD),
asthma and interstitial lung diseases are frequently occurring disorders with a polygenic …

Modeling psychotic disorders: Environment x environment interaction

K Murlanova, MV Pletnikov - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Schizophrenia is a major psychotic disorder with multifactorial etiology that includes
interactions between genetic vulnerability and environmental risk factors. In addition …

[HTML][HTML] Integrating-omics approaches into population-based studies of endocrine disrupting chemicals: A scoping review

L Maitre, P Jedynak, M Gallego, L Ciaran… - Environmental …, 2023 - Elsevier
Health effects of endocrine disrupting chemicals (EDCs) are challenging to detect in the
general population. Omics technologies become increasingly common to identify early …

Parkinson's disease is predominantly a genetic disease

SY Lim, C Klein - Journal of Parkinson's Disease, 2024 - content.iospress.com
The discovery of a pathogenic variant in the alpha-synuclein (SNCA) gene in the Contursi
kindred in 1997 indisputably confirmed a genetic cause in a subset of Parkinson's disease …

Exploring Single-Cell Exposomics by Mass Spectrometry

P Gao - Environmental Science & Technology, 2023 - ACS Publications
Single-cell exposomics, a revolutionary approach that investigates cell–environment
interactions at cellular and subcellular levels, stands distinct from conventional bulk …

Air pollution exposure and cardiometabolic risk

S Rajagopalan, RD Brook, PRVO Salerno… - The Lancet Diabetes & …, 2024 - thelancet.com
Summary The Global Burden of Disease assessment estimates that 20% of global type 2
diabetes cases are related to chronic exposure to particulate matter (PM) with a diameter of …

Precision public health in the era of genomics and big data

MC Roberts, KE Holt, G Del Fiol, AA Baccarelli… - Nature Medicine, 2024 - nature.com
Precision public health (PPH) considers the interplay between genetics, lifestyle and the
environment to improve disease prevention, diagnosis and treatment on a population level …

Rebalancing commercial and public interests in prioritizing biomedical, social and environmental aspects of health through defining and managing conflicts of interest

BK Redman - Frontiers in Medicine, 2023 - frontiersin.org
Biomedical research is intended to benefit human beings and their health. Toward that end,
scientific norms involve examining and criticizing the work of others and prioritizing …