Combining de novo and reference-guided assembly with scaffold_builder

GGZ Silva, BE Dutilh, TD Matthews, K Elkins… - Source code for biology …, 2013 - Springer
Genome sequencing has become routine, however genome assembly still remains a
challenge despite the computational advances in the last decade. In particular, the …

MeDuSa: a multi-draft based scaffolder

E Bosi, B Donati, M Galardini, S Brunetti… - …, 2015 - academic.oup.com
Motivation: Completing the genome sequence of an organism is an important task in
comparative, functional and structural genomics. However, this remains a challenging issue …

Diversity and evolution of secondary metabolism in the marine actinomycete genus Salinispora

N Ziemert, A Lechner, M Wietz… - Proceedings of the …, 2014 - National Acad Sciences
Access to genome sequence data has challenged traditional natural product discovery
paradigms by revealing that the products of most bacterial biosynthetic pathways have yet to …

PirVP genes causing AHPND identified in a new Vibrio species (Vibrio punensis) within the commensal Orientalis clade

L Restrepo, B Bayot, S Arciniegas, L Bajaña… - Scientific reports, 2018 - nature.com
Acute hepatopancreatic necrosis disease (AHPND) has extended rapidly, causing alarming
shrimp mortalities. Initially, the only known causative agent was Vibrio parahaemolyticus …

Genome mining identifies cepacin as a plant-protective metabolite of the biopesticidal bacterium Burkholderia ambifaria

AJ Mullins, JAH Murray, MJ Bull, M Jenner… - Nature …, 2019 - nature.com
Beneficial microorganisms are widely used in agriculture for control of plant pathogens, but
a lack of efficacy and safety information has limited the exploitation of multiple promising …

Comparative genomics reveals phylogenetic distribution patterns of secondary metabolites in Amycolatopsis species

M Adamek, M Alanjary, H Sales-Ortells, M Goodfellow… - BMC genomics, 2018 - Springer
Background Genome mining tools have enabled us to predict biosynthetic gene clusters that
might encode compounds with valuable functions for industrial and medical applications …

A post-assembly genome-improvement toolkit (PAGIT) to obtain annotated genomes from contigs

MT Swain, IJ Tsai, SA Assefa, C Newbold… - Nature protocols, 2012 - nature.com
Genome projects now produce draft assemblies within weeks owing to advanced high-
throughput sequencing technologies. For milestone projects such as Escherichia coli or …

Genome-Guided Insights into the Plant Growth Promotion Capabilities of the Physiologically Versatile Bacillus aryabhattai Strain AB211

C Bhattacharyya, U Bakshi, I Mallick… - Frontiers in …, 2017 - frontiersin.org
Bacillus aryabhattai AB211 is a plant growth promoting, Gram-positive firmicute, isolated
from the rhizosphere of tea (Camellia sinensis), one of the oldest perennial crops and a …

A comparative and functional genomics analysis of the genus Romboutsia provides insight into adaptation to an intestinal lifestyle

J Gerritsen, B Hornung, J Ritari, L Paulin, GT Rijkers… - BioRxiv, 2019 - biorxiv.org
Cultivation-independent surveys have shown that the recently described genus Romboutsia
within the family Peptostreptococcaceae is more diverse than previously acknowledged. The …

Genomic Insights Into the Antifungal Activity and Plant Growth-Promoting Ability in Bacillus velezensis CMRP 4490

GM Teixeira, M Mosela, MLA Nicoletto… - Frontiers in …, 2021 - frontiersin.org
The main objective of this study was to evaluate Bacillus velezensis strain CMRP 4490
regarding its ability to inhibit soil-borne plant pathogens and to increase plant growth. The …