Cochlear health and cochlear-implant function

KC Schvartz-Leyzac, DJ Colesa, DL Swiderski… - Journal of the …, 2023 - Springer
The cochlear implant (CI) is widely considered to be one of the most innovative and
successful neuroprosthetic treatments developed to date. Although outcomes vary, CIs are …

Speech and language outcomes in adults and children with cochlear implants

TN Tamati, DB Pisoni, AC Moberly - Annual Review of …, 2022 - annualreviews.org
Cochlear implants (CIs) represent a significant engineering and medical milestone in the
treatment of hearing loss for both adults and children. In this review, we provide a brief …

Effects of electrode location on estimates of neural health in humans with cochlear implants

KC Schvartz-Leyzac, TA Holden, TA Zwolan… - Journal of the …, 2020 - Springer
There are a number of psychophysical and electrophysiological measures that are
correlated with SGN density in animal models, and these same measures can be performed …

[HTML][HTML] Speech perception performance in cochlear implant recipients correlates to the number and synchrony of excited auditory nerve fibers derived from …

Y Dong, JJ Briaire, HC Stronks, JHM Frijns - Ear and Hearing, 2023 - journals.lww.com
Objectives: Many studies have assessed the performance of individuals with cochlear
implants (CIs) with electrically evoked compound action potentials (eCAPs). These eCAP …

[HTML][HTML] Evaluating psychophysical polarity sensitivity as an indirect estimate of neural status in cochlear implant listeners

KN Jahn, JG Arenberg - Journal of the Association for Research in …, 2019 - Springer
The physiological integrity of spiral ganglion neurons is presumed to influence cochlear
implant (CI) outcomes, but it is difficult to measure neural health in CI listeners. Modeling …

[HTML][HTML] The panoramic ECAP method: estimating patient-specific patterns of current spread and neural health in cochlear implant users

C Garcia, T Goehring, S Cosentino, RE Turner… - Journal of the …, 2021 - Springer
The knowledge of patient-specific neural excitation patterns from cochlear implants (CIs) can
provide important information for optimizing efficacy and improving speech perception …

Prediction of the functional status of the cochlear nerve in individual cochlear implant users using machine learning and electrophysiological measures

J Skidmore, L Xu, X Chao, WJ Riggs, A Pellittieri… - Ear and …, 2021 - journals.lww.com
Objectives: This study aimed to create an objective predictive model for assessing the
functional status of the cochlear nerve (CN) in individual cochlear implant (CI) users. Design …

Neurotrophin gene therapy to promote survival of spiral ganglion neurons after deafness

PA Leake, O Akil, H Lang - Hearing research, 2020 - Elsevier
Hearing impairment is a major health and economic concern worldwide. Currently, the
cochlear implant (CI) is the standard of care for remediation of severe to profound hearing …

[HTML][HTML] Interpreting the effect of stimulus parameters on the electrically evoked compound action potential and on neural health estimates

T Brochier, CM McKay, RP Carlyon - … of the Association for Research in …, 2021 - Springer
Variations in the condition of the neural population along the length of the cochlea can
degrade the spectral and temporal representation of sounds conveyed by CIs, thereby …

[HTML][HTML] Changes in the electrically evoked compound action potential over time after implantation and subsequent deafening in guinea pigs

D Ramekers, H Benav, SFL Klis, H Versnel - Journal of the Association for …, 2022 - Springer
The electrically evoked compound action potential (eCAP) is a direct measure of the
responsiveness of the auditory nerve to electrical stimulation from a cochlear implant (CI) …