[HTML][HTML] Locus of (IL-9) control: IL9 epigenetic regulation in cellular function and human disease

A Son, I Baral, GH Falduto, DM Schwartz - Experimental & Molecular …, 2024 - nature.com
Abstract Interleukin-9 (IL-9) is a multifunctional cytokine with roles in a broad cross-section of
human diseases. Like many cytokines, IL-9 is transcriptionally regulated by a group of …

Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of TH9 cells to promote allergic inflammation

A Son, F Meylan, J Gomez-Rodriguez, Z Kaul… - Nature …, 2023 - nature.com
Allergic diseases are a major global health issue. Interleukin (IL)-9-producing helper T (TH9)
cells promote allergic inflammation, yet TH9 cell effector functions are incompletely …

[HTML][HTML] Tox induces T cell IL-10 production in a BATF-dependent manner

DA Canaria, JA Rodriguez, L Wang, FJ Yeo… - Frontiers in …, 2023 - frontiersin.org
Tox is a member of the high mobility group (HMG)-Box transcription factors and plays
important roles in thymic T cell development. Outside of the thymus, however, Tox is also …

哮喘表型中CD4+ T 细胞亚群的研究综述: 分子机制和生物治疗选择

赵艳红, 王传萍 - 上海交通大学学报(医学版), 2023 - xuebao.shsmu.edu.cn
哮喘是一种慢性炎症性气道疾病, 主要由不同的CD4+ T 细胞亚群[辅助性T 细胞(helper T cell,
Th 细胞)] 驱动. CD4+ T 细胞亚群是一类重要的免疫细胞, 能够分泌多种细胞因子 …

TRANSCRIPTIONAL CONTROL OF T HELPER CELL DIFFERENTIATION

DAC Gonzalez - 2023 - hammer.purdue.edu
IL-9-producing CD4+ T helper (Th9) cells contribute to inflammatory responses during
infection, anti-cancer responses and autoimmune disease. Thus, elucidating the signals that …

Review of CD4+ T cell subsets in asthma phenotypes: molecular mechanisms and biologic treatment options

Z Yanhong, W Chuanping - Journal of Shanghai Jiao Tong …, 2023 - xuebao.shsmu.edu.cn
Asthma is a chronic inflammatory airway disease, mainly driven by different CD4+ T cell
subsets [helper T cell (Th cell)]. CD4+ T cell subsets are a type of important immune cells …

Étude des fonctions indépendantes de l'inflammasome de NLRP3 dans les lymphocytes T et de leurs impacts sur la réponse immunitaire antitumorale

C Hibos - 2023 - theses.hal.science
Dans la grande majorité des cancers, les lymphocytes T CD8 infiltrant la tumeur sont
associés à un meilleur pronostic. Le rôle des T CD4 est, quant à lui, plus contrasté. Au cours …