Next-generation tissue-engineered heart valves with repair, remodelling and regeneration capacity

ES Fioretta, SE Motta, V Lintas, S Loerakker… - Nature Reviews …, 2021 - nature.com
Valvular heart disease is a major cause of morbidity and mortality worldwide. Surgical valve
repair or replacement has been the standard of care for patients with valvular heart disease …

Scaling digital twins from the artisanal to the industrial

SA Niederer, MS Sacks, M Girolami… - Nature Computational …, 2021 - nature.com
Mathematical modeling and simulation are moving from being powerful development and
analysis tools towards having increased roles in operational monitoring, control and …

The openCARP simulation environment for cardiac electrophysiology

G Plank, A Loewe, A Neic, C Augustin… - Computer methods and …, 2021 - Elsevier
Abstract Background and Objective: Cardiac electrophysiology is a medical specialty with a
long and rich tradition of computational modeling. Nevertheless, no community standard for …

Artificial intelligence and machine learning in arrhythmias and cardiac electrophysiology

AK Feeny, MK Chung, A Madabhushi… - Circulation …, 2020 - Am Heart Assoc
Artificial intelligence (AI) and machine learning (ML) in medicine are currently areas of
intense exploration, showing potential to automate human tasks and even perform tasks …

Machine learning in arrhythmia and electrophysiology

NA Trayanova, DM Popescu, JK Shade - Circulation research, 2021 - Am Heart Assoc
Machine learning (ML), a branch of artificial intelligence, where machines learn from big
data, is at the crest of a technological wave of change sweeping society. Cardiovascular …

Artificial intelligence in the diagnosis and management of arrhythmias

VD Nagarajan, SL Lee, JL Robertus… - European heart …, 2021 - academic.oup.com
The field of cardiac electrophysiology (EP) had adopted simple artificial intelligence (AI)
methodologies for decades. Recent renewed interest in deep learning techniques has …

Predicting atrial fibrillation recurrence by combining population data and virtual cohorts of patient-specific left atrial models

CH Roney, I Sim, J Yu, M Beach, A Mehta… - Circulation …, 2022 - Am Heart Assoc
Background: Current ablation therapy for atrial fibrillation is suboptimal, and long-term
response is challenging to predict. Clinical trials identify bedside properties that provide only …

Computational models of atrial fibrillation: Achievements, challenges, and perspectives for improving clinical care

J Heijman, H Sutanto, HJGM Crijns… - Cardiovascular …, 2021 - academic.oup.com
Despite significant advances in its detection, understanding and management, atrial
fibrillation (AF) remains a highly prevalent cardiac arrhythmia with a major impact on …

Critical appraisal of technologies to assess electrical activity during atrial fibrillation: A position paper from the European heart rhythm association and European …

NMS De Groot, D Shah, PM Boyle, E Anter… - EP …, 2022 - academic.oup.com
We aim to provide a critical appraisal of basic concepts underlying signal recording and
processing technologies applied for (i) atrial fibrillation (AF) mapping to unravel AF …

The physics of heart rhythm disorders

WJ Rappel - Physics reports, 2022 - Elsevier
The global burden caused by cardiovascular disease is substantial, with heart disease
representing the most common cause of death around the world. There remains a need to …