Pulmonary phenotypes of bronchopulmonary dysplasia in the preterm infant

M Gilfillan, DM Vineet Bhandari MD - Seminars in perinatology, 2023 - Elsevier
Bronchopulmonary dysplasia (BPD) remains the most common complication of premature
birth, imposing a significant and potentially life-long burden on patients and their families …

Patent ductus arteriosus and bronchopulmonary dysplasia–associated pulmonary hypertension: a bayesian meta-analysis

E Villamor, E van Westering-Kroon… - JAMA Network …, 2023 - jamanetwork.com
Importance Bronchopulmonary dysplasia (BPD) is often associated with pulmonary vascular
disease and secondary pulmonary hypertension (PH). The pathogenesis of BPD-associated …

[HTML][HTML] Association of patent ductus arteriosus with fetal factors and endotypes of prematurity

E Villamor, M Borges-Lujan, G Gonzalez-Luis - Seminars in Perinatology, 2023 - Elsevier
During fetal life, the ductus arteriosus (DA) acquires the mechanisms for its postnatal closure
following a thorough developmental program. This program can be interrupted by preterm …

Bronchopulmonary dysplasia: ongoing challenges from definitions to clinical care

S Nuthakki, K Ahmad, G Johnson… - Journal of Clinical …, 2023 - mdpi.com
Bronchopulmonary dysplasia (BPD) is the most common complication of extreme
prematurity. Its etiology is multifactorial and is attributed to genetic susceptibility to prenatal …

Endothelial dysfunction in preterm infants: The hidden legacy of uteroplacental pathologies

GS Amelio, L Provitera, G Raffaeli, M Tripodi… - Frontiers in …, 2022 - frontiersin.org
Millions of infants are born prematurely every year worldwide. Prematurity, particularly at
lower gestational ages, is associated with high mortality and morbidity and is a significant …

Association of funisitis with short-term outcomes of prematurity: a frequentist and bayesian meta-analysis

TM Hundscheid, MJ Huizing, E Villamor-Martinez… - Antioxidants, 2023 - mdpi.com
The fetal systemic inflammatory response associated with intra-amniotic inflammation may
play a key role in the pathogenesis of complications of preterm birth. Funisitis is the …

Exploring the association of male sex with adverse outcomes in severe bronchopulmonary dysplasia: a retrospective, multicenter cohort study

JD Hammond II, MJ Kielt, S Conroy, K Lingappan… - Chest, 2024 - Elsevier
Background Bronchopulmonary dysplasia (BPD) is a significant contributor to morbidity and
death in infants who are born premature. Male sex is an independent risk factor for the …

Combining lung ultrasound and oscillatory mechanics for assessing lung disease in very preterm infants

C Rigotti, E Zannin, RL Dellacà, ML Ventura - Pediatric Research, 2024 - nature.com
Background We investigated whether combining lung ultrasound scores (LUSs) and
respiratory system reactance (Xrs) measured by respiratory oscillometry explains the …

Placing Ureaplasma within the Context of Bronchopulmonary Dysplasia Endotypes and Phenotypes

K Van Mechelen, E van Westering-Kroon, M Hütten… - Children, 2023 - mdpi.com
Different pathophysiological pathways (endotypes), leading to very preterm birth may result
in distinct clinical phenotypes of bronchopulmonary dysplasia (BPD). Ureaplasma is a …

Insulin-like growth factor-1 replacement therapy after extremely premature birth: An opportunity to optimize lifelong lung health by preserving the natural sequence of …

BW Kramer, S Abman, M Daly, AH Jobe… - Paediatric respiratory …, 2023 - Elsevier
The past decades have seen markedly improved survival of increasingly immature preterm
infants, yet major health complications persist. This is particularly true for bronchopulmonary …