Oral delivery of natural active small molecules by polymeric nanoparticles for the treatment of inflammatory bowel diseases

M Zu, Y Ma, B Cannup, D Xie, Y Jung, J Zhang… - Advanced Drug Delivery …, 2021 - Elsevier
The incidence of inflammatory bowel disease (IBD) is rapidly rising throughout the world.
Although tremendous efforts have been made, limited therapeutics are available for IBD …

Biodegradable polymeric nanoparticles loaded with flavonoids: A promising therapy for inflammatory bowel disease

M Li, Y Liu, B Weigmann - International Journal of Molecular Sciences, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is a group of disorders that cause chronic non-specific
inflammation in the gastrointestinal (GI) tract, primarily affecting the ileum and colon. The …

Calcium Tungstate Microgel enhances the delivery and colonization of Probiotics during Colitis via Intestinal ecological niche occupancy

J Yang, M Peng, S Tan, S Ge, L Xie, T Zhou… - ACS Central …, 2023 - ACS Publications
The effective delivery and colonization of probiotics are recommended for therapeutic
interventions during colitis, the efficacy of which is hampered by abnormally colonized …

[HTML][HTML] Intracellular hydrogelation of macrophage conjugated probiotics for hitchhiking delivery and combined treatment of colitis

J Wang, D Hu, Q Chen, T Liu, X Zhou, Y Xu, H Zhou… - Materials Today Bio, 2023 - Elsevier
Immune cell membrane coated nanomedicine was developed to neutralize cytokines via
receptor-ligand interaction, which showed potential for the treatment of inflammatory bowel …

[HTML][HTML] A close view on histopathological changes in inflammatory bowel disease, a narrative review

L Kellermann, LB Riis - Digestive Medicine Research, 2021 - dmr.amegroups.org
Optimal management of inflammatory bowel disease (IBD) requires a multidisciplinary team
approach, including specialists in the fields of gastroenterology, surgery, radiology and …

Self-assembled micelle derived from pterostilbene ameliorate acute inflammatory bowel disease

H Zhong, H Zhang, Y Hu, S He, H Qu, J He… - International Journal of …, 2023 - Elsevier
PEGylated pterostilbene micelle (PTENPs) with higher bioavailability, biocompatibility, and
water solubility were prepared. Then we detected the therapeutic effects in the treatment of …

Causality of genetically determined blood metabolites on inflammatory bowel disease: a two-sample Mendelian randomization study

X Long, Y Zhang, M Liu, Z Liu, L Xia, X Xu, M Wu - Scientific Reports, 2024 - nature.com
Inflammatory bowel disease (IBD) is a chronic and recurrent inflammatory disease of the
gastrointestinal tract, including two subtypes: Crohn's disease (CD) and ulcerative colitis …

Investigating regulatory patterns of NLRP3 Inflammasome features and association with immune microenvironment in Crohn's disease

H Wu, R Zeng, X Qiu, K Chen, Z Zhuo, K Guo… - Frontiers in …, 2023 - frontiersin.org
Introduction Crohn's disease is characterized of dysregulated inflammatory and immune
reactions. The role of the NOD-like receptor family, pyrin domain-containing 3 (NLRP3) …

Development of a convolutional neural network-based colonoscopy image assessment model for differentiating crohn's disease and ulcerative colitis

L Wang, L Chen, X Wang, K Liu, T Li, Y Yu… - Frontiers in …, 2022 - frontiersin.org
Objective Evaluation of the endoscopic features of Crohn's disease (CD) and ulcerative
colitis (UC) is the key diagnostic approach in distinguishing these two diseases. However …

Diagnostic yield and technical performance of the novel motorized spiral enteroscopy compared with single-balloon enteroscopy in suspected Crohn's disease: a …

P Pal, P Vishwakarma, AP Singh, PM Reddy… - Gastrointestinal …, 2023 - Elsevier
Background and Aims Both single-balloon enteroscopy (SBE) and the novel motorized
spiral enteroscopy (NMSE) are effective techniques for device-assisted enteroscopy (DAE) …