Alzheimer's disease (AD) is the leading cause of dementia in elderly people. Amyloid beta
(Aβ) deposits and neurofibrillary tangles are the major pathological features in an …

Induced pluripotent stem cell (iPSC) technologies have provided in vitro models of
inaccessible human cell types, yielding new insights into disease mechanisms especially for …

Cadmium (Cd), a category I human carcinogen, is a well-known widespread environmental
pollutant. Chronic Cd exposure affects different organs and tissues, such as the central …

Post-mortem studies allow for the direct investigation of brain tissue in those with autism and
related disorders. Several review articles have focused on aspects of post-mortem …

Synapses are the site for brain communication where information is transmitted between
neurons and stored for memory formation. Synaptic degeneration is a global and early …

It has been reported that disordered Cu metabolism is associated with several
neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease …

Alzheimer's disease (AD) is a chronic neurodegenerative disease and the most frequent
cause of progressive dementia in senior adults. It is characterized by memory loss and …

Structural and functional integrity of the cerebral vasculature ensures proper brain
development and function, as well as healthy aging. The inability of the brain to store energy …

Parkinson's disease (PD) is considered the most common disorder of synucleinopathy,
which is characterised by intracellular inclusions of aggregated and misfolded α-synuclein …

The genetics underlying autism spectrum disorder (ASD) is complex and heterogeneous,
and de novo variants are found in genes converging in functional biological processes …