[HTML][HTML] Next-generation sequencing shows the genomic features of ovarian clear cell cancer and compares the genetic architectures of high-grade serous ovarian …

M Gan, Z Tai, Y Yu, C Zhang, J Xu - PeerJ, 2023 - peerj.com
Ovarian clear cell carcinoma (OCCC) is a special histological type of epithelial ovarian
cancer (EOC) that is not derived from epithelial cells of the ovarian or fallopian tube as the …

TG468: a text graph convolutional network for predicting clinical response to immune checkpoint inhibitor therapy

K Wang, J Shi, X Tong, N Qu, X Kong… - Briefings in …, 2024 - academic.oup.com
Enhancing cancer treatment efficacy remains a significant challenge in human health.
Immunotherapy has witnessed considerable success in recent years as a treatment for …

Antitumor immunity and prognosis value elicited by FAT3 and LRP1B co-mutation in endometrial cancer

Z Jiang, M Zhu, L Zhang, H Cui, R Jiang, Y Yang - Gynecologic Oncology, 2024 - Elsevier
Abstract Objective: FAT3 and LRP1B are two tumor suppressor genes with high mutation
frequency in multiple cancer types, we sought to investigate the prognostic and …

Osteosarcoma's genetic landscape painted by genes' mutations

W Urban, D Krzystańska, M Piekarz… - Acta Biochimica …, 2023 - abp.ptbioch.edu.pl
Purpose: Osteosarcoma (OS) is one of the most common primary bone tumors. Direct
pathogenesis remains unknown, however, genes' mutations are proven to participate in the …

[HTML][HTML] Determining the prognosis of Lung cancer from mutated genes using a deep learning survival model: a large multi-center study

J Peng, L Xiao, H Zhu, L Han, H Ma - Cancer Cell International, 2023 - Springer
Background Gene status has become the focus of prognosis prediction. Furthermore, deep
learning has frequently been implemented in medical imaging to diagnose, prognosticate …

[HTML][HTML] TMBur: a distributable tumor mutation burden approach for whole genome sequencing

E Titmuss, RD Corbett, S Davidson, S Abbasi… - BMC Medical …, 2022 - Springer
Background Tumor mutation burden (TMB) is a key characteristic used in a tumor-type
agnostic context to inform the use of immune checkpoint inhibitors (ICI). Accurate and …

[HTML][HTML] Molecular Signature Expands the Landscape of Driver Negative Thyroid Cancers

LV Bim, TNR Carneiro, VC Buzatto, GA Colozza-Gama… - Cancers, 2021 - mdpi.com
Simple Summary Thyroid cancer is the most common endocrine malignancy. However, the
cytological diagnosis of certain malignant thyroid tumors and their benign counterparts is a …

[HTML][HTML] Whole-genome characterization of large-cell lung carcinoma: A comparative analysis based on the histological classification

X Wu, J Yin, Y Deng, Y Zu - Frontiers in Genetics, 2023 - frontiersin.org
Background: According to the 2015 World Health Organization classification, large cell
neuroendocrine carcinoma (LCNEC) was isolated from Large-cell lung cancer (LCLC) …

Survey of genomic and physiological characteristics for survival in lymphoma: The NCI genomic data portal

D Hollar - Current Problems in Cancer, 2023 - Elsevier
Lymphoma represents a myriad collection of neoplasms that impact lymphocytes. This
cancer often involves disrupted cytokine, immune surveillance, and gene regulatory …

Genetic alteration and their significance on clinical events in small cell lung cancer

S Jiao, X Zhang, D Wang, H Fu… - Cancer Management and …, 2023 - Taylor & Francis
Introduction Small cell lung cancer (SCLC), an aggressive subtype of lung cancer
characterized by the development of neuroendocrine tumors, is prone to distant metastasis …