Null hypothesis significance testing (NHST) has several shortcomings that are likely
contributing factors behind the widely debated replication crisis of (cognitive) neuroscience …

Research Methodology is meant to provide a broad guideline to facilitate and steer the
whole of a research activity in any discipline. With the ambit and amount of research …

Progress in science relies in part on generating hypotheses with existing observations and
testing hypotheses with new observations. This distinction between postdiction and …

A valuable overview of the most important ideas and results in statistical modeling Written by
a highly-experienced author, Foundations of Linear and Generalized Linear Models is a …

Reproducible climate reconstructions of the Common Era (1 CE to present) are key to
placing industrial-era warming into the context of natural climatic variability. Here we present …

This paper presents an overview of the current state of the art in multiple testing in genomics
data from a user's perspective. We describe methods for familywise error control, false …

I describe the background for the paper 'Controlling the false discovery rate: a new and
powerful approach to multiple comparisons' by Benjamini and Hochberg that was published …

The article considers whether B ig D ata, in the form of data‐driven science, will enable the
discovery, or appraisal, of universal scientific theories, instrumentalist tools, or inductive …

Whole genome bisulphite sequencing (WGBS) permits the genome-wide study of single
molecule methylation patterns. One of the key goals of mammalian cell-type identity studies …

The challenges associated with handling uncertain data, in particular with querying and
mining, are finding increasing attention in the research community. Here we focus on …