Gross total vs. subtotal resection on survival outcomes in elderly patients with high-grade glioma: a systematic review and meta-analysis

Q Han, H Liang, P Cheng, H Yang, P Zhao - Frontiers in oncology, 2020 - frontiersin.org
Background: The optimal strategy for the management of high-grade glioma in the elderly
(≥ 60.0 years) remains controversial, especially regarding the effects of surgical extent on …

Delirium in neurosurgery: a systematic review and meta-analysis

PR Kappen, E Kakar, CMF Dirven, M Van der Jagt… - Neurosurgical …, 2022 - Springer
Delirium is a frequent occurring complication in surgical patients. Nevertheless, a scientific
work-up of the clinical relevance of delirium after intracranial surgery is lacking. We …

Glioblastoma in the elderly: Review of molecular and therapeutic aspects

F Bruno, A Pellerino, R Palmiero, L Bertero… - Biomedicines, 2022 - mdpi.com
Glioblastoma (GBM) is the most aggressive primary brain tumour. As GBM incidence is
associated with age, elderly people represent a consistent subgroup of patients. Elderly …

The incidence and predictors of postoperative delirium after brain tumor resection in adults: a cross-sectional survey

H Chen, H Jiang, B Chen, L Fan, W Shi, Y Jin, X Ren… - World Neurosurgery, 2020 - Elsevier
Background Postoperative delirium (POD) describes a multifactorial disease process
occurring after surgery. However, few studies have focused on patients undergoing brain …

Music to prevent deliriUm during neuroSurgerY (MUSYC): a single-centre, prospective randomised controlled trial

PR Kappen, MI Mos, J Jeekel, CMF Dirven… - BMJ open, 2023 - bmjopen.bmj.com
Objectives Delirium is a serious complication following neurosurgical procedures. We
hypothesise that the beneficial effect of music on a combination of delirium-eliciting factors …

Disparities in health care determine prognosis in newly diagnosed glioblastoma

A Chandra, JW Rick, C Dalle Ore, D Lau… - Neurosurgical …, 2018 - thejns.org
OBJECTIVE Glioblastoma (GBM) is an aggressive brain malignancy with a short overall
patient survival, yet there remains significant heterogeneity in outcomes. Although access to …

Postoperative delirium in glioblastoma patients: risk factors and prognostic implications

PM Flanigan, A Jahangiri, D Weinstein, F Dayani… - …, 2018 - journals.lww.com
BACKGROUND: Delirium is a postoperative neurological morbidity in glioblastoma whose
risk factors, incidence, and prognostic implications remain undefined. OBJECTIVE: To …

Recurrent glioblastomas in the elderly after maximal first-line treatment: does preserved overall condition warrant a maximal second-line treatment?

M Zanello, A Roux, R Ursu, S Peeters… - Journal of Neuro …, 2017 - Springer
A growing literature supports maximal safe resection followed by standard combined
chemoradiotherapy (ie maximal first-line therapy) for selected elderly glioblastoma patients …

Is age an additional factor in the treatment of elderly patients with glioblastoma? A new stratification model: an Italian Multicenter Study

T Ius, T Somma, R Altieri, FF Angileri… - Neurosurgical …, 2020 - thejns.org
OBJECTIVE Approximately half of glioblastoma (GBM) cases develop in geriatric patients,
and this trend is destined to increase with the aging of the population. The optimal strategy …

Current clinical management of elderly patients with glioma

A Pellerino, F Bruno, V Internò, R Rudà… - Expert Review of …, 2020 - Taylor & Francis
Introduction The incidence of gliomas is increasing in elderly patients. Clinical factors, such
as age, performance status, and comorbidities contribute when choosing adequate …