Lung tissue has a certain regenerative ability and triggers repair procedures after injury.
Under controllable conditions, lung tissue can restore normal structure and function …

The human lung is a relatively quiescent organ in the normal healthy state but contains
stem/progenitor cells that contribute to normal tissue maintenance and either repair or …

Lack of CFTR (cystic fibrosis transmembrane conductance regulator) affects the
transcriptome, composition, and function of large and small airway epithelia in people with …

Loss of secretory IgA (SIgA) is common in chronic obstructive pulmonary disease (COPD)
small airways and likely contributes to disease progression. We hypothesized that loss of …

Lung cancer has become the primary cause of cancer-related deaths because of its high
recurrence rate, ability to metastasise easily, and propensity to develop drug resistance. The …

Airway hillocks are stratified epithelial structures of unknown function. Hillocks persist for
months and have a unique population of basal stem cells that express genes associated …

Background Chronic obstructive pulmonary disease (COPD) is a kind of chronic lung
diseases with the characteristics of airway remodeling and airflow obstruction. Magnesium …

Research Impact Cigarette smoke (CS) exposure is strongly associated with chronic
obstructive pulmonary disease (COPD). In respiratory airways, CS exposure disrupts airway …

Background Increased airway resistance and hyperinflation in chronic obstructive
pulmonary disease (COPD) are associated with increased mechanical stress that modulate …

Acute lung injury (ALI) is a specific form of lung damage caused by different infectious and
non-infectious agents, including SARS-CoV-2, leading to severe respiratory and systemic …