[HTML][HTML] Cpt1a alleviates cigarette smoke‑induced chronic obstructive pulmonary disease
L Li, Y Zhang, J Gong, G Yang… - Experimental and …, 2023 - spandidos-publications.com
The current study aimed to determine the expression of carnitine palmitoyltransferase 1A
(Cpt1a) in the lung tissue of chronic obstructive pulmonary disease (COPD) patients and its …
(Cpt1a) in the lung tissue of chronic obstructive pulmonary disease (COPD) patients and its …
[HTML][HTML] Small airway susceptibility to chemical and particle injury
LFH Fransen, MO Leonard - Respiration, 2022 - karger.com
Small airways (SA) in humans are commonly defined as those conducting airways< 2 mm in
diameter. They are susceptible to particle-and chemical-induced injury and play a major role …
diameter. They are susceptible to particle-and chemical-induced injury and play a major role …
[HTML][HTML] The NOTCH3 downstream target HEYL is required for efficient human airway basal cell differentiation
M Bodas, B Subramaniyan, AR Moore, JP Metcalf… - Cells, 2021 - mdpi.com
Basal cells (BCs) are stem/progenitor cells of the mucociliary airway epithelium, and their
differentiation is orchestrated by the NOTCH signaling pathway. NOTCH3 receptor signaling …
differentiation is orchestrated by the NOTCH signaling pathway. NOTCH3 receptor signaling …
Exposure to a combination of silica nanoparticles and low-dose radiation aggravates lung fibrosis in mice via gut microbiota modulation
Z Ju, G Ren, M Zhou, J Jing, J Xiang, X Liu… - Environmental …, 2020 - pubs.rsc.org
Exposure to silica nanoparticles (SNPs) causes lung fibrosis and threatens human health.
However, it is unknown if low-dose radiation (LDR) exposure exacerbates SNP-induced …
However, it is unknown if low-dose radiation (LDR) exposure exacerbates SNP-induced …
Promising Intestinal Microbiota Associated with Clinical Characteristics of COPD Through Integrated Bioinformatics Analysis
T Lai, C Luo, Y Yuan, J Fang, Y Wang… - … Journal of Chronic …, 2024 - Taylor & Francis
Introduction Chronic obstructive pulmonary disease (COPD), an incurable chronic
respiratory disease, has become a major public health problem. The relationship between …
respiratory disease, has become a major public health problem. The relationship between …
Exportin XPO6 upregulation activates the TLR2/MyD88/NF-κB signaling by facilitating TLR2 mRNA nuclear export in COPD pulmonary monocytes
Y Wu, Y Gou, T Wang, P Li, Y Li, X Lu, W Li… - International …, 2024 - Elsevier
Chronic obstructive pulmonary disease (COPD) poses a significant health threat
characterized by lung inflammation primarily triggered by pulmonary monocytes. Despite the …
characterized by lung inflammation primarily triggered by pulmonary monocytes. Despite the …
Expression profile of IL-17 in lung tissues of patients with lung cancer and COPD and clinical significance
T Yang - Cellular and Molecular Biology, 2022 - mail.cellmolbiol.org
The purpose of this experiment to analyze the expression and clinical significance of
interleukin-17 (IL-17) in lung tissue of lung cancer patients with chronic obstructive …
interleukin-17 (IL-17) in lung tissue of lung cancer patients with chronic obstructive …
Airway Basal Stem Cells in COVID-19 Exhibit a Proinflammatory Signature and Impaired Mucocililary Differentiation
Airway basal stem cells (BSCs) play a critical role in epithelial regeneration. Whether
coronavirus disease (COVID-19) affects BSC function is unknown. Here, we derived BSC …
coronavirus disease (COVID-19) affects BSC function is unknown. Here, we derived BSC …
[HTML][HTML] Mechanical stretch promotes apoptosis and impedes ciliogenesis of primary human airway basal stem cells
LQ Lin, HK Zeng, YL Luo, DF Chen, XQ Ma… - Respiratory …, 2023 - Springer
Background Airway basal stem cells (ABSCs) have self-renewal and differentiation abilities.
Although an abnormal mechanical environment related to chronic airway disease (CAD) can …
Although an abnormal mechanical environment related to chronic airway disease (CAD) can …
Transcriptomics and metabolomics revealed the pulmonary protective mechanism of Xixin-Ganjiang Herb Pair for warming the lungs to dissolve phlegm in COPD rats
P Huang, B Duan, D Li, Y Duan, Z Zhou, L Han… - … of Chromatography B, 2023 - Elsevier
Abstract Xixin-Ganjiang Herb Pair (XGHP), a classic combination treatment to warm the
lungs and dissolve phlegm, is widely used in the treatment of various pulmonary diseases …
lungs and dissolve phlegm, is widely used in the treatment of various pulmonary diseases …