Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …

In a diabetic milieu high levels of reactive oxygen species (ROS) are induced. This
contributes to the vascular complications of diabetes. Recent studies have shown that ROS …

The increasing global prevalence of type 2 diabetes mellitus (T2DM) and chronic kidney
disease (CKD) has prompted research efforts to tackle the growing epidemic of diabetic …

Elastography-based imaging techniques have received substantial attention in recent years
for non-invasive assessment of tissue mechanical properties. These techniques take …

The path that individuals take from dependency in childhood to independence in adulthood
is now a longer and more complicated one than at any other point in history (Arnett 2014) …

Background Chronic kidney disease (CKD) is a public health problem largely caused by
diabetes. The epidemiology of diabetes mellitus–related CKD (CKD-DM) could provide …

Background Current anemia therapies for patients with non–dialysis-dependent CKD may
require injection and medical visits. Roxadustat, an oral hypoxia-inducible factor prolyl …

Diabetic nephropathy (DN) is one of the most feared diabetic chronic microvascular
complications and the major cause of end-stage renal disease (ESRD). The classical …

Ferroptosis is a novel type of programmed cell death characterized by iron-dependent
accumulation of lipid hydroperoxides to lethal levels. Accumulative studies have indicated …

Summary Each year, the American Heart Association (AHA), in conjunction with the Centers
for Disease Control and Prevention, the National Institutes of Health, and other government …