Lipid management in patients with chronic kidney disease

CJ Ferro, PB Mark, M Kanbay, P Sarafidis… - Nature Reviews …, 2018 - nature.com
An increased risk of cardiovascular disease, independent of conventional risk factors, is
present even at minor levels of renal impairment and is highest in patients with end-stage …

[HTML][HTML] Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis

G Hindy, DJ Tyrrell, A Vasbinder, C Wei… - The Journal of …, 2022 - Am Soc Clin Investig
People with kidney disease are disproportionately affected by atherosclerosis for unclear
reasons. Soluble urokinase plasminogen activator receptor (suPAR) is an immune-derived …

Bio-inspired hemocompatible surface modifications for biomedical applications

M Douglass, M Garren, R Devine, A Mondal… - Progress in materials …, 2022 - Elsevier
When blood first encounters the artificial surface of a medical device, a complex series of
biochemical reactions is triggered, potentially resulting in clinical complications such as …

Social determinants of racial disparities in CKD

JM Norton, MM Moxey-Mims, PW Eggers… - Journal of the …, 2016 - journals.lww.com
Significant disparities in CKD rates and outcomes exist between black and white Americans.
Health disparities are defined as health differences that adversely affect disadvantaged …

[HTML][HTML] Hypertension and cardiomyopathy associated with chronic kidney disease: epidemiology, pathogenesis and treatment considerations

JP Law, L Pickup, D Pavlovic, JN Townend… - Journal of Human …, 2023 - nature.com
Chronic kidney disease (CKD) is a complex condition with a prevalence of 10–15%
worldwide. An inverse-graded relationship exists between cardiovascular events and …

Arteriovenous fistula maturation, functional patency, and intervention rates

TS Huber, SA Berceli, ST Scali, D Neal… - JAMA …, 2021 - jamanetwork.com
Importance National initiatives have emphasized the use of autogenous arteriovenous
fistulas (AVFs) for hemodialysis, but their purported benefits have been questioned …

Diabetic nephropathy: is there a role for oxidative stress?

MK Sagoo, L Gnudi - Free Radical Biology and Medicine, 2018 - Elsevier
Oxidative stress has been implicated in the pathophysiology of diabetic nephropathy.
Studies in experimental animal models of diabetes strongly implicate oxidant species as a …

[HTML][HTML] Peritoneal dialysis–related infection rates and outcomes: results from the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS)

J Perl, DS Fuller, BA Bieber, N Boudville… - American Journal of …, 2020 - Elsevier
Rationale & Objective Peritoneal dialysis (PD)-related peritonitis carries high morbidity for
PD patients. Understanding the characteristics and risk factors for peritonitis can guide …

[HTML][HTML] Reducing major risk factors for chronic kidney disease

VA Luyckx, KR Tuttle, G Garcia-Garcia… - Kidney international …, 2017 - Elsevier
Chronic kidney disease (CKD) is a global public health concern and a key determinant of
poor health outcomes. While the burden of CKD is reasonably well defined in developed …

Cardiac metabolic remodelling in chronic kidney disease

N Patel, MM Yaqoob, D Aksentijevic - Nature Reviews Nephrology, 2022 - nature.com
Chronic kidney disease (CKD) affects millions of people globally and, for most patients, the
risk of developing cardiovascular disease is higher than that of progression to kidney failure …