Helminth-derived biomacromolecules as therapeutic agents for treating inflammatory and infectious diseases: What lessons do we get from recent findings?
Despite the tremendous progress in healthcare sectors, a number of life-threatening
infectious, inflammatory, and autoimmune diseases are continuously challenging mankind …
infectious, inflammatory, and autoimmune diseases are continuously challenging mankind …
[HTML][HTML] The impact of helminth-induced immunity on infection with bacteria or viruses
H Chen, Z Cao, M Liu, MS Diamond, X Jin - Veterinary Research, 2023 - Springer
Different human and animal pathogens trigger distinct immune responses in their hosts. The
infection of bacteria or viruses can trigger type I pro-inflammatory immune responses (eg …
infection of bacteria or viruses can trigger type I pro-inflammatory immune responses (eg …
Helminth alleviates COVID-19-related cytokine storm in an IL-9-dependent way
Z Cao, J Wang, X Liu, Y Liu, F Li, M Liu, S Chiu, X Jin - Mbio, 2024 - Am Soc Microbiol
Hyperactivation of pro-inflammatory type 1 cytokines (eg, tumor necrosis factor alpha [TNF-α]
and interferon gamma [IFN-γ]) mirrors the inflammation of coronavirus disease 2019 …
and interferon gamma [IFN-γ]) mirrors the inflammation of coronavirus disease 2019 …
[HTML][HTML] Negative association between ascaris lumbricoides seropositivity and Covid-19 severity: insights from a study in Benin
T Adjobimey, J Meyer, A Hennenfent, AJ Bara… - Frontiers in …, 2023 - frontiersin.org
Introduction The COVID-19 pandemic has had devastating effects worldwide, but the
trajectory of the pandemic has been milder in Low-and-Middle-Income Countries (LMICs) …
trajectory of the pandemic has been milder in Low-and-Middle-Income Countries (LMICs) …
[HTML][HTML] Infection with soil-transmitted helminths and their impact on coinfections
J Schlosser-Brandenburg, A Midha, RM Mugo… - Frontiers in …, 2023 - frontiersin.org
The most important soil-transmitted helminths (STHs) affecting humans are roundworms,
whipworms, and hookworms, with a large proportion of the world's population infected with …
whipworms, and hookworms, with a large proportion of the world's population infected with …
The Potential Nexus between Helminths and SARS‐CoV‐2 Infection: A Literature Review
HM Al-Kuraishy, AI Al-Gareeb, L Alkazmi… - Journal of …, 2023 - Wiley Online Library
Chronic helminth infections (CHIs) can induce immunological tolerance through the
upregulation of regulatory T cells. In coronavirus disease 2019 (COVID‐19), abnormal …
upregulation of regulatory T cells. In coronavirus disease 2019 (COVID‐19), abnormal …
[HTML][HTML] Filariasis research–from basic research to drug development and novel diagnostics, over a decade of research at the Institute for Medical Microbiology …
Filariae are vector borne parasitic nematodes, endemic in tropical and subtropical regions
causing avoidable infections ranging from asymptomatic to stigmatizing and disfiguring …
causing avoidable infections ranging from asymptomatic to stigmatizing and disfiguring …
[HTML][HTML] Trichinella spiralis Infection Inhibits the Efficacy of RBD Protein of SARS-CoV-2 Vaccination via Regulating Humoral and Cellular Immunity
F Zhu, W Zheng, Y Gong, J Zhang, Y Yu, J Zhang… - Vaccines, 2024 - mdpi.com
Vaccines are the most effective and feasible way to control pathogen infection. Helminths
have been reported to jeopardize the protective immunity mounted by several vaccines …
have been reported to jeopardize the protective immunity mounted by several vaccines …
[HTML][HTML] Antigens from the Helminth Fasciola hepatica Exert Antiviral Effects against SARS-CoV-2 In Vitro
J Serrat, C Francés-Gómez, D Becerro-Recio… - International journal of …, 2023 - mdpi.com
SARS-CoV-2, the causal agent of COVID-19, is a new coronavirus that has rapidly spread
worldwide and significantly impacted human health by causing a severe acute respiratory …
worldwide and significantly impacted human health by causing a severe acute respiratory …
[HTML][HTML] COVID-19 morbidity in lower versus higher income populations underscores the need to restore lost biodiversity of eukaryotic symbionts
W Parker, E Patel, K Jirků-Pomajbíková, JD Laman - Iscience, 2023 - cell.com
The avoidance of infectious disease by widespread use of 'systems hygiene', defined by
hygiene-enhancing technology such as sewage systems, water treatment facilities, and …
hygiene-enhancing technology such as sewage systems, water treatment facilities, and …