Cryptococcus neoformans and Cryptococcus gattii are the two etiologic agents of
cryptococcosis. They belong to the phylum Basidiomycota and can be readily distinguished …

Pulmonary cryptococcosis is an important opportunistic invasive mycosis in
immunocompromised patients, but it is also increasingly seen in immunocompetent patients …

Understanding of the taxonomy and phylogeny of Cryptococcus gattii has been advanced by
modern molecular techniques. C. gattii probably diverged from Cryptococcus neoformans …

Melanin is a unique pigment with myriad functions that is found in all biological kingdoms. It
is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) …

Abstract Cryptococcus neoformans (Cn) and Cryptococcus gattii (Cg) cause neurological
disease and cross the BBB as free cells or in mononuclear phagocytes via the Trojan horse …

In Aspergillus fumigatus, the conidial surface contains dihydroxynaphthalene (DHN)-
melanin. Six-clustered gene products have been identified that mediate sequential catalysis …

The emergence of distinct populations of Cryptococcus gattii in the temperate North
American Pacific Northwest (PNW) was surprising, as this species was previously thought to …

Cryptococcus neoformans causes fatal fungal meningoencephalitis. Here, we study the
roles played by fungal kinases and transcription factors (TFs) in blood-brain barrier (BBB) …

Melanins are ubiquitous pigments found in all kingdoms of life. Most organisms use them for
protection from environmental stress, although some fungi employ melanins as virulence …

Cryptococcus gattii is a fungal pathogen of humans, causing pulmonary infections in
otherwise healthy hosts. To characterize genomic variation among the four major lineages of …