A guide to the composition and functions of the extracellular matrix

NK Karamanos, AD Theocharis, Z Piperigkou… - The FEBS …, 2021 - Wiley Online Library
Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …

Recent progress in materials chemistry to advance flexible bioelectronics in medicine

G Balakrishnan, J Song, C Mou… - Advanced …, 2022 - Wiley Online Library
Designing bioelectronic devices that seamlessly integrate with the human body is a
technological pursuit of great importance. Bioelectronic medical devices that reliably and …

Ultra-durable cell-free bioactive hydrogel with fast shape memory and on-demand drug release for cartilage regeneration

Y Yang, X Zhao, S Wang, Y Zhang, A Yang… - Nature …, 2023 - nature.com
Osteoarthritis is a worldwide prevalent disease that imposes a significant socioeconomic
burden on individuals and healthcare systems. Achieving cartilage regeneration in patients …

Mimicking the hierarchical organization of natural collagen: toward the development of ideal scaffolding material for tissue regeneration

L Salvatore, N Gallo, ML Natali, A Terzi… - … in Bioengineering and …, 2021 - frontiersin.org
Biological materials found in living organisms, many of which are proteins, feature a
complex hierarchical organization. Type I collagen, a fibrous structural protein ubiquitous in …

Promotion of skin regeneration through co-axial electrospun fibers loaded with basic fibroblast growth factor

J Chen, G Zhang, Y Zhao, M Zhou, A Zhong… - … composites and hybrid …, 2022 - Springer
Cutaneous wound healing is complex, requiring a coordinated response by growth factors,
drugs, and resident cells of the skin. To simulate native extracellular matrix, electrospun …

Polymeric and biological membranes for organ-on-a-chip devices

K Corral-Nájera, G Chauhan… - Microsystems & …, 2023 - nature.com
Membranes are fundamental elements within organ-on-a-chip (OOC) platforms, as they
provide adherent cells with support, allow nutrients (and other relevant molecules) to …

Nanocomposite bioprinting for tissue engineering applications

K Loukelis, ZA Helal, AG Mikos, M Chatzinikolaidou - Gels, 2023 - mdpi.com
Bioprinting aims to provide new avenues for regenerating damaged human tissues through
the controlled printing of live cells and biocompatible materials that can function …

Distinct effects of different matrix proteoglycans on collagen fibrillogenesis and cell-mediated collagen reorganization

D Chen, LR Smith, G Khandekar, P Patel, CK Yu… - Scientific reports, 2020 - nature.com
The extracellular matrix (ECM) is a complex mixture composed of fibrillar collagens as well
as additional protein and carbohydrate components. Proteoglycans (PGs) contribute to the …

[HTML][HTML] BMSC-derived extracellular matrix better optimizes the microenvironment to support nerve regeneration

S Wang, C Zhu, B Zhang, J Hu, J Xu, C Xue, S Bao… - Biomaterials, 2022 - Elsevier
A favorable microenvironment plays an important role in nerve regeneration. Extracellular
matrix (ECM) derived from cultured cells or natural tissues can facilitate nerve regeneration …

Mimicked spinal cord fibers trigger axonal regeneration and remyelination after injury

Z Chen, Z Sun, Y Fan, M Yin, C Jin, B Guo, Y Yin… - ACS …, 2023 - ACS Publications
Spinal cord injury (SCI) causes tissue structure damage and composition changes of the
neural parenchyma, resulting in severe consequences for spinal cord function. Mimicking …