Abstract Interleukin-33 (IL-33), a member of the IL-1 family, and its cognate receptor,
Interleukin-1 receptor like-1 (IL-1RL1 or ST2), are susceptibility genes for childhood asthma …

Bronchodilators remain the cornerstone of the treatment of airway disorders such as asthma
and chronic obstructive pulmonary disease (COPD). There is therefore considerable interest …

Individuals differ substantially in their response to pharmacological treatment. Personalized
medicine aspires to embrace these inter-individual differences and customize therapy by …

The advent of the knowledge on human genetics, by the identification of disease-associated
variants, culminated in the understanding of human variability. With the genetic knowledge …

Who do you think of when autism is mentioned? Maybe a familiar trope comes to mind: an
eccentric white man, perhaps in the vein of The Big Bang Theory's socially naive genius, Dr …

More than a decade has passed since the finalization of the Human Genome Project. Omics
technologies made a huge leap from trendy and very expensive to routinely executed and …

There is increasing international policy and clinical interest in developing learning health
systems and delivering precision medicine, which it is hoped will help reduce variation in the …

Allergic diseases are highly complex with respect to pathogenesis, inflammation, and
response to treatment. Current efforts for allergic disease diagnosis have focused on clinical …

To the editor, Asthma, one of the most common chronic diseases in childhood, is caused by
interactions between genes and environmental factors. The mainstay of treatment is daily …

Objective To review the state of omics science specific to asthma and allergic diseases and
discuss the current and potential applicability of omics in clinical disease prediction …