Medicine, even from the earliest days of artificial intelligence (AI) research, has been one of
the most inspiring and promising domains for the application of AI-based approaches …

The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

Biomarkers are naturally-occurring characteristics by which a particular pathological process
or disease can be identified or monitored. They can reflect past environmental exposures …

Cancer onset and progression have been linked to oxidative stress by increasing DNA
mutations or inducing DNA damage, genome instability, and cell proliferation and therefore …

Why do we grow up to look, act, and feel as we do? Through most of the twentieth century,
scientists and laypeople answered this question by referring to two factors alone: our …

Epigenetic and genetic alterations contribute to cancer initiation and progression.
Epigenetics refers to the study of heritable changes in gene expression without alterations in …

Abstract DNA methylation, through 5-methyl-and 5-hydroxymethylcytosine (5mC and 5hmC),
is considered to be one of the principal interfaces between the genome and our …

Epigenetic mechanisms play a pivotal role in the expression of genes and can be influenced
by both the quality and quantity of diet. Dietary compounds such as sulforaphane (SFN) …

The identification of mutations and deletions in the SMARCB1 locus in chromosome band
22q11. 2 in pediatric rhabdoid tumors provided the first evidence for the involvement of the …

The transformation of normal cells into cancer cells and maintenance of the malignant state
and phenotypes are associated with genetic and epigenetic deregulations, altered cellular …