Key Proteins of Replication Stress Response and Cell Cycle Control as Cancer Therapy Targets
AI Khamidullina, YE Abramenko, AV Bruter… - International Journal of …, 2024 - mdpi.com
Replication stress (RS) is a characteristic state of cancer cells as they tend to exchange
precision of replication for fast proliferation and increased genomic instability. To overcome …
precision of replication for fast proliferation and increased genomic instability. To overcome …
Genomics and Artificial Intelligence: Prostate Cancer
EY Wong, TN Chu, SS Ladi-Seyedian - Urologic Clinics, 2023 - urologic.theclinics.com
Management of patients with prostate cancer (PCa) is often challenging due to the
difference in the biology of cancer between patients and the various genetic alterations …
difference in the biology of cancer between patients and the various genetic alterations …
Machine learning-based investigation of regulated cell death for predicting prognosis and immunotherapy response in glioma patients
W Zhang, R Dang, H Liu, L Dai, H Liu, AA Adegboro… - Scientific Reports, 2024 - nature.com
Glioblastoma is a highly aggressive and malignant type of brain cancer that originates from
glial cells in the brain, with a median survival time of 15 months and a 5-year survival rate of …
glial cells in the brain, with a median survival time of 15 months and a 5-year survival rate of …
Architecting the metabolic reprogramming survival risk framework in LUAD through single-cell landscape analysis: three-stage ensemble learning with genetic …
X Sun, M Nong, F Meng, X Sun, L Jiang, Z Li… - Journal of Translational …, 2024 - Springer
Recent studies have increasingly revealed the connection between metabolic
reprogramming and tumor progression. However, the specific impact of metabolic …
reprogramming and tumor progression. However, the specific impact of metabolic …
Computer-aided drug discovery strategies for novel therapeutics for prostate cancer leveraging next-generating sequencing data
Introduction Prostate cancer (PC) is the most common malignancy and accounts for a
significant proportion of cancer deaths among men. Although initial therapy success can …
significant proportion of cancer deaths among men. Although initial therapy success can …
Sustained pigmentation causes DNA damage and invokes translesion polymerase Polκ for repair in melanocytes
M Ghazi, S Khanna, Y Subramaniam… - Nucleic Acids …, 2023 - academic.oup.com
Melanin protects skin cells from ultraviolet radiation-induced DNA damage. However,
intermediates of eumelanin are highly reactive quinones that are potentially genotoxic. In …
intermediates of eumelanin are highly reactive quinones that are potentially genotoxic. In …
[HTML][HTML] A DNA Replication Stress-Based Prognostic Model for Lung Adenocarcinoma
S Shi, G Wen, C Lei, J Chang, X Yin, X Liu… - Acta Naturae, 2023 - ncbi.nlm.nih.gov
Tumor cells endure continuous DNA replication stress, which opens the way to cancer
development. Despite previous research, the prognostic implications of DNA replication …
development. Despite previous research, the prognostic implications of DNA replication …
Predictive AI Model to Manage Transcriptomics-Based Transition of Hormone-Naive to Castrate-Resistant Prostate Cancer: An Opportunity Towards Precision …
N Singh, D Annan - Global journal of Business and Integral Security, 2023 - gbis.ch
Precision medicine is a groundbreaking approach to the treatment of prostate cancer. It
involves tailoring medical decisions and therapies to individual patients based on their …
involves tailoring medical decisions and therapies to individual patients based on their …