Molecular mechanisms of antibiotic resistance revisited

EM Darby, E Trampari, P Siasat, MS Gaya… - Nature Reviews …, 2023 - nature.com
Antibiotic resistance is a global health emergency, with resistance detected to all antibiotics
currently in clinical use and only a few novel drugs in the pipeline. Understanding the …

Exploring phytochemicals for combating antibiotic resistance in microbial pathogens

T Khare, U Anand, A Dey, YG Assaraf… - Frontiers in …, 2021 - frontiersin.org
Antibiotic resistance or microbial drug resistance is emerging as a serious threat to human
healthcare globally, and the multidrug-resistant (MDR) strains are imposing major hurdles to …

High Prevalence of Multidrug-Resistant Klebsiella pneumoniae Harboring Several Virulence and β-Lactamase Encoding Genes in a Brazilian Intensive Care Unit

RL Ferreira, BCM Da Silva, GS Rezende… - Frontiers in …, 2019 - frontiersin.org
Klebsiella pneumoniae is an important opportunistic pathogen that commonly causes
nosocomial infections and contributes to substantial morbidity and mortality. We sought to …

Molecular Mechanisms, Epidemiology, and Clinical Importance of β-Lactam Resistance in Enterobacteriaceae

G De Angelis, P Del Giacomo, B Posteraro… - International journal of …, 2020 - mdpi.com
Despite being members of gut microbiota, Enterobacteriaceae are associated with many
severe infections such as bloodstream infections. The β-lactam drugs have been the …

Freshwater viral metagenome reveals novel and functional phage-borne antibiotic resistance genes

K Moon, JH Jeon, I Kang, KS Park, K Lee, CJ Cha… - Microbiome, 2020 - Springer
Background Antibiotic resistance developed by bacteria is a significant threat to global
health. Antibiotic resistance genes (ARGs) spread across different bacterial populations …

[HTML][HTML] Invited review: Antimicrobial resistance in bovine mastitis pathogens: A review of genetic determinants and prevalence of resistance in European countries

A Naranjo-Lucena, R Slowey - Journal of Dairy Science, 2023 - Elsevier
Antimicrobial resistance is an urgent and growing problem worldwide, both for human and
animal health. In the animal health sector actions have been taken as concerns grow …

Antimicrobial Resistance in Escherichia coli Strains Isolated from Humans and Pet Animals

N Puvača, R de Llanos Frutos - Antibiotics, 2021 - mdpi.com
Throughout scientific literature, we can find evidence that antimicrobial resistance has
become a big problem in the recent years on a global scale. Public healthcare systems all …

Comprehensive study of antimicrobial susceptibility pattern and extended spectrum beta-lactamase (ESBL) prevalence in bacteria isolated from urine samples

MJ Gharavi, J Zarei, P Roshani-Asl, Z Yazdanyar… - Scientific reports, 2021 - nature.com
Nowadays, increasing extended-spectrum β-lactamase (ESBL)-producing bacteria have
become a global concern because of inducing resistance toward most of the antimicrobial …

Risk Factors of Extended-Spectrum Beta-Lactamases-Producing Escherichia coli Community Acquired Urinary Tract Infections: A Systematic Review

S Larramendy, V Deglaire, P Dusollier… - Infection and Drug …, 2020 - Taylor & Francis
Purpose The prevalence of extended-spectrum beta-lactamase-producing Escherichia coli
(ESBL-EC) has been increasing worldwide since the early 2000s. E. coli is found in 70–90 …

The threat of multidrug-resistant/extensively drug-resistant Gram-negative respiratory infections: another pandemic

D Reynolds, JP Burnham, CV Guillamet… - European …, 2022 - Eur Respiratory Soc
Antibiotic resistance is recognised as a global threat to human health by national healthcare
agencies, governments and medical societies, as well as the World Health Organization …