Cardiovascular diseases create an important burden on the public health systems,
especially in the elderly, mostly because this group of patients frequently suffer from multiple …

MEDLINE, MEDLINE In-Process, CINAHL, and EMBASE databases were used for the initial
literature search. The search was limited to articles published in the English language …

Níveis de evidência Nível A Dados obtidos a partir de múltiplos estudos randomizados de
bom porte, concordantes e/ou de meta-análise robusta de estudos clínicos randomizados …

Patients with widespread atherosclerosis such as peripheral artery disease (PAD) have a
high risk of cardiovascular and limb symptoms and complications, which affects their quality …

Level of evidence Level A Data obtained from multiple concordant large randomized trials
and/or robust meta-analysis of randomized clinical trials Level B Data obtained from less …

Background Lipedema is a loose connective tissue disease predominantly in women
identified by increased nodular and fibrotic adipose tissue on the buttocks, hips and limbs …

Background and aims It is unclear whether improvements in the detection/treatment of
peripheral artery disease (PAD) affect overall survival and morbidity. We undertook a …

There is an accumulating body of literature reporting on dietary flavonoid intake and the risk
of cardiovascular disease (CVD) in prospective cohort studies. This makes apparent the …

Sauna use, sometimes referred to as “sauna bathing,” is characterized by short-term passive
exposure to high temperatures, typically ranging from 45° C to 100° C (113° F to 212° F) …

Primarily used in the treatment of intermittent claudication, cilostazol is a 2-oxyquinolone
derivative that works through the inhibition of phosphodiesterase III and related increases in …