A considerable number of human diseases have an inflammatory component, and a key
mediator of immune activation and inflammation is inducible nitric oxide synthase (iNOS) …

Since its discovery, the STAT3 transcription factor has been extensively studied for its
function as a transcriptional regulator and its role as a mediator of development, normal …

Abstract Non-thermal plasma (NTP), an engineered technology to generate reactive
species, induces ferroptosis and/or apoptosis specifically in various-type cancer cells. NTP …

Immunotherapy approaches for pancreatic ductal adenocarcinoma (PDAC) have met with
limited success. It has been postulated that a low mutation load may lead to a paucity of T …

Colorectal cancer (CRC) is the one of the leading causes of cancer-related deaths in the
world. CRC is responsible for more than 600,000 deaths annually and incidence rates are …

Mulberry (Morus alba L.) is a flowering tree traditionally used in Chinese herbal medicine.
Mulberry leaf flavonoids (MLFs) have been reported to exert important anti-inflammatory and …

Chlorogenic acid (CGA) is a bioactive substance with anti-inflammatory activities. Clusters of
CD36 have been suggested to be widely involved in inflammatory damage. However, the …

Background & Aims Known genetic factors explain only a small fraction of genetic variation
in colorectal cancer (CRC). We conducted a genome-wide association study to identify risk …

The high efficacy of therapeutic cancer vaccines in preclinical studies has yet to be fully
achieved in clinical trials. Tumor immune suppression is a critical factor that hampers the …

Radiosensitizers are compounds or nanostructures, which can improve the efficiency of
ionizing radiation to kill cells. Radiosensitization increases the susceptibility of cancer cells …