Asthma is an inflammatory disorder of the conducting airways that has strong association
with allergic sensitization. The disease is characterized by a polarized Th-2 (T-helper-2) …

Evidence-based practice is an important component of health care service delivery.
However, there is a tendency, embodied in tools such as Grades of Recommendation …

Summary Background The Single combination budesonide–formoterol inhaler Maintenance
And Reliever Therapy (SMART) regimen reduces severe asthma exacerbations in patients …

In less than half a century, allergy, originally perceived as a rare disease, has become a
major public health threat, today affecting the lives of more than 60 million people in Europe …

BACKGROUND: The role of IgE in patients with severe asthma is not fully understood.
OBJECTIVE: We sought to investigate whether IgE to Staphylococcus aureus enterotoxins …

Real-world research can use observational or clinical trial designs, in both cases putting
emphasis on high external validity, to complement the classical efficacy randomized …

To cite this article: Ohta K, Bousquet P‐J, Aizawa H, Akiyama K, Adachi M, Ichinose M,
Ebisawa M, Tamura G, Nagai A, Nishima S, Fukuda T, Morikawa A, Okamoto Y, Kohno Y …

Asthma was previously defined as an allergic Th2‐mediated inflammatory immune disorder.
Recently, this paradigm has been challenged because not all pathological changes …

Purpose: Assess the clinical and economic consequences associated with an early versus
late diagnosis in patients with COPD. Patients and methods: In a retrospective …

目的探讨匹多莫德治疗对支气管哮喘患儿免疫功能的影响, 并对其疗效进行分析. 方法选择2011
年1 月至2013 年1 月该院收治的90 例支气管哮喘患儿, 将哮喘患儿分为匹多莫德观察组和对照 …