Mass spectrometry analysis of human tear fluid biomarkers specific for ocular and systemic diseases in the context of 3P medicine

X Zhan, J Li, Y Guo, O Golubnitschaja - EPMA Journal, 2021 - Springer
Over the last two decades, a large number of non-communicable/chronic disorders reached
an epidemic level on a global scale such as diabetes mellitus type 2, cardio-vascular …

Caution,“normal” BMI: health risks associated with potentially masked individual underweight—EPMA Position Paper 2021

O Golubnitschaja, A Liskova, L Koklesova, M Samec… - EPMA Journal, 2021 - Springer
An increasing interest in a healthy lifestyle raises questions about optimal body weight.
Evidently, it should be clearly discriminated between the standardised “normal” body weight …

Protective effects of flavonoids against mitochondriopathies and associated pathologies: focus on the predictive approach and personalized prevention

L Koklesova, A Liskova, M Samec, K Zhai… - International Journal of …, 2021 - mdpi.com
Multi-factorial mitochondrial damage exhibits a “vicious circle” that leads to a progression of
mitochondrial dysfunction and multi-organ adverse effects. Mitochondrial impairments …

unique metabolic signature of proliferative retinopathy in the tear fluid of diabetic patients with comorbidities—preliminary data for PPPM validation

M Kropp, E De Clerck, TTKS Vo, G Thumann… - EPMA Journal, 2023 - Springer
Abstract Type 2 diabetes (T2DM) defined as the adult-onset type that is primarily not insulin-
dependent, comprises over 95% of all diabetes mellitus (DM) cases. According to global …

Making a complex dental care tailored to the person: population health in focus of predictive, preventive and personalised (3P) medical approach

VV Tachalov, LY Orekhova, TV Kudryavtseva… - EPMA Journal, 2021 - Springer
An evident underestimation of the targeted prevention of dental diseases is strongly
supported by alarming epidemiologic statistics globally. For example, epidemiologists …

Challenging management of severe chronic disorders in acute pandemic situation: Chronic liver disease under COVID-19 pandemic as the proof-of-principle model to …

L Skladany, T Koller, S Adamcova Selcanova… - EPMA Journal, 2021 - Springer
Chronic liver disease management is a comprehensive approach requiring multi-
professional expertise and well-orchestrated healthcare measures thoroughly organized by …

Diagnosing hospital bacteraemia in the framework of predictive, preventive and personalised medicine using electronic health records and machine learning …

O Garnica, D Gómez, V Ramos, JI Hidalgo… - EPMA Journal, 2021 - Springer
Background The bacteraemia prediction is relevant because sepsis is one of the most
important causes of morbidity and mortality. Bacteraemia prognosis primarily depends on a …

Changes in Dental Biofilm Proteins' Secondary Structure in Groups of People with Different Cariogenic Situations in the Oral Cavity and Using Medications by Means …

P Seredin, D Goloshchapov, V Kashkarov… - International Journal of …, 2023 - mdpi.com
This work unveils the idea that the cariogenic status of the oral cavity (the presence of active
caries lesions) can be predicted via a lineshape analysis of the infrared spectral signatures …

Automated detection of nine infantile fundus diseases and conditions in retinal images using a deep learning system

Y Liu, H Xie, X Zhao, J Tang, Z Yu, Z Wu, R Tian… - EPMA Journal, 2024 - Springer
Abstract Purpose We developed an Infant Retinal Intelligent Diagnosis System (IRIDS), an
automated system to aid early diagnosis and monitoring of infantile fundus diseases and …

Ideal cardiovascular health metrics and life expectancy free of cardiovascular diseases: a prospective cohort study

Q Tian, S Chen, J Zhang, C Li, S Wu, Y Wang, Y Wang - EPMA Journal, 2023 - Springer
Objectives Whether cardiovascular health (CVH) metrics impact longevity with and without
cardiovascular diseases (CVDs) has not been well established. This study aimed to …