The Neurobiology and Genetics of Suicide and Attempted Suicide:: A Focus on the Serotonergic System
Numerous abnormalities have been found in the serotonergic system in suicide attempters
and completers. There is considerable evidence that the serotonergic system is partly under …
and completers. There is considerable evidence that the serotonergic system is partly under …
Serotonin transporter: a potential substrate in the biology of suicide
DC Purselle, CB Nemeroff - Neuropsychopharmacology, 2003 - nature.com
Suicide is a serious public health problem in the US, yet its neurobiological underpinnings
are poorly understood. Suicide is highly correlated with depressive symptoms, and …
are poorly understood. Suicide is highly correlated with depressive symptoms, and …
A serotonin transporter gene promoter polymorphism (5-HTTLPR) and prefrontal cortical binding in major depression and suicide
JJ Mann, Y Huang, MD Underwood… - Archives of general …, 2000 - jamanetwork.com
Background Major depression and suicide are associated with fewer serotonin transporter
(5-HTT) sites. The 5′-flanking promoter region of the 5-HTT gene has a biallelic …
(5-HTT) sites. The 5′-flanking promoter region of the 5-HTT gene has a biallelic …
Localized alterations in pre-and postsynaptic serotonin binding sites in the ventrolateral prefrontal cortex of suicide victims
Altered serotonin indices have been reported in the brain of suicide victims. We sought to
localize the changes in presynaptic and postsynaptic serotonin receptors and identify an …
localize the changes in presynaptic and postsynaptic serotonin receptors and identify an …
Right-lateralised central processing for pain of nitroglycer-induced cluster headache
JC Hsieh, J Hannerz, M Ingvar - Pain, 1996 - Elsevier
Recent functional brain imaging studies with positron emission tomography (PET) suggest a
preference of the right hemisphere, especially the anterior cingulate cortex (ACC), in …
preference of the right hemisphere, especially the anterior cingulate cortex (ACC), in …
Effects of quitting smoking on EEG activation and attention last for more than 31 days and are more severe with stress, dependence, DRD2 A1 allele, and depressive …
DG Gilbert, FJ McClernon… - Nicotine & Tobacco …, 2004 - academic.oup.com
Abstract Changes in physiology and attentional performance associated with smoking
abstinence were characterized in 67 female smokers during low-stress and high-stress …
abstinence were characterized in 67 female smokers during low-stress and high-stress …
[HTML][HTML] Morphometry of the dorsal raphe nucleus serotonergic neurons in suicide victims
MD Underwood, AA Khaibulina, SP Ellis, A Moran… - Biological …, 1999 - Elsevier
Background: The serotonin deficiency hypothesis of suicide has been important
heuristically. Few studies have directly examined the brainstem dorsal raphe nucleus (DRN) …
heuristically. Few studies have directly examined the brainstem dorsal raphe nucleus (DRN) …
CSF serotonin, 5-hydroxyindolacetic acid and neuropeptide Y levels in severe major depressive disorder
C Hou, F Jia, Y Liu, L Li - Brain research, 2006 - Elsevier
Serotonin (5-HT) and 5-hydroxyindolacetic acid (5-HIAA) have been the putative markers of
MDD. Neuropeptide Y (NPY) may have an important role in the pathophysiology of major …
MDD. Neuropeptide Y (NPY) may have an important role in the pathophysiology of major …
Postmortem Findings in Suicide Victims. Implications for in Vivo Imaging Studiesa
V Arango, MD Underwood… - Annals of the New York …, 1997 - Wiley Online Library
Alterations in serotonergic and noradrenergic receptor binding in membrane homogenates
from the brain of suicide victims suggest a biological substrate for the vulnerability to commit …
from the brain of suicide victims suggest a biological substrate for the vulnerability to commit …
Adrenal weight and morphology in victims of completed suicide
Several lines of evidence have implicated hypothalamic-pituitary-adrenal (HPA) axis
dysfunction in major depression and suicidal behavior. In the present study, the weight and …
dysfunction in major depression and suicidal behavior. In the present study, the weight and …