Acute pancreatitis may be associated with both local and systemic complications. Systemic
injury manifests in the form of organ failure, which is seen in approximately 20% of all cases …

Premature activation of digestive enzymes in the pancreas has been linked to development
of pancreatitis for more than a century. Recent development of novel models to study the …

Recent advances challenge the long-believed trypsin-centered understanding of
pancreatitis. It is becoming increasingly clear that activation of intense inflammatory …

Rationale: Acute pancreatitis (AP) is a serious acute condition affecting the abdomen and
shows high morbidity and mortality rates. Its global incidence has increased in recent years …

Objective: The aim of this study was to compare and validate the different classifications of
severity in acute pancreatitis (AP) and to investigate which characteristics of the disease are …

Acute pancreatitis is a disease associated with suffering and high lethality. Although the
disease mechanism is unclear, phospholipase A2 (PLA2) produced by pancreatic acinar …

Background Pancreatitis in cats, although commonly diagnosed, still presents many
diagnostic and management challenges. Objective To summarize the current literature as it …

Cell death and inflammation are key pathologic responses of acute pancreatitis (AP), the
leading cause of hospital admissions for gastrointestinal disorders. It is becoming …

While most cases of pancreatitis in dogs are thought to be idiopathic, potential risk factors
are identified. In this article we provide a state‐of‐the‐art overview of suspected risk factors …

Background: There is no curative therapy for severe acute pancreatitis (SAP) due to poor
understanding of its molecular mechanisms. Endoplasmic reticulum (ER) stress is involved …