Optimising antimicrobial selection and duration in the treatment of febrile neutropenia in children

JE Morgan, B Phillips, GM Haeusler… - Infection and drug …, 2021 - Taylor & Francis
Febrile neutropenia (FN) is a frequent complication of cancer treatment in children. Owing to
the potential for overwhelming bacterial sepsis, the recognition and management of FN …

[HTML][HTML] Marine antimicrobial peptide epinecidin-1 inhibits proliferation induced by lipoteichoic acid and causes cell death in non-small cell lung cancer cells via …

HH Yu, LY Wu, PL Hsu, CW Lee, BC Su - Probiotics and Antimicrobial …, 2023 - Springer
Non-small cell lung cancer (NSCLC) is among the deadliest cancers worldwide. Despite the
recent introduction of several new therapeutic approaches for the disease, improvements in …

Nurses are underutilised in antimicrobial stewardship–Results of a multisite survey in paediatric and adult hospitals

M Mostaghim, T Snelling, B McMullan… - Infection, Disease & …, 2017 - Elsevier
Objectives Explore perceptions and attitudes of nurses in regard to antimicrobial
stewardship (AMS), their roles as nurses, and identify differences in perceptions and …

[HTML][HTML] Predicting infectious complications in children with cancer: an external validation study

GM Haeusler, KA Thursky, F Mechinaud… - British journal of …, 2017 - nature.com
Background: The aim of this study was to validate the 'Predicting Infectious ComplicatioNs in
Children with Cancer'(PICNICC) clinical decision rule (CDR) that predicts microbiologically …

Blood transcriptomics identifies immune signatures indicative of infectious complications in childhood cancer patients with febrile neutropenia

GM Haeusler, AL Garnham… - Clinical & …, 2022 - Wiley Online Library
Objectives Febrile neutropenia (FN) is a major cause of treatment disruption and unplanned
hospitalization in childhood cancer patients. This study investigated the transcriptome of …

Management of fever and neutropenia in children with cancer: A survey of Australian and New Zealand practice

GM Haeusler, MA Slavin, PA Bryant… - … of paediatrics and …, 2018 - Wiley Online Library
Aim Variation in the management of fever and neutropenia (FN) in children is well
described. The aim of this study was to explore the current management of FN across …

[HTML][HTML] Procalcitonin and interleukin-10 may assist in early prediction of bacteraemia in children with cancer and febrile neutropenia

M Doerflinger, GM Haeusler, CSN Li-Wai-Suen… - Frontiers in …, 2021 - frontiersin.org
Objectives Febrile neutropenia (FN) causes treatment disruption and unplanned
hospitalization in children with cancer. Serum biomarkers are infrequently used to stratify …

Epidemiology of Febrile Neutropenia Episodes with Gram-Negative Bacteria Infection in Patients Who Have Undergone Chemotherapy for Hematologic Malignancies …

Y Zhang, Y Zheng, F Dong, H Ma, L Zhu… - Infection and drug …, 2020 - Taylor & Francis
Background The epidemiology of Gram-negative bacteria in patients with febrile
neutropenia (FN) and their susceptibility to initial empirical antibiotic therapy is key to …

External validation of six pediatric fever and neutropenia clinical decision rules

GM Haeusler, KA Thursky, MA Slavin… - The Pediatric …, 2018 - journals.lww.com
Background: Fever and neutropenia (FN) clinical decision rules (CDRs) are recommended
to help distinguish children with cancer at high and low risk of severe infection. The aim of …

Prevalence, epidemiology, etiology, and sensitivity of invasive bacterial infections in pediatric patients undergoing oncological treatment: a multicenter nationwide …

O Zajac-Spychala, J Wachowiak… - Microbial Drug …, 2021 - liebertpub.com
Background: Infectious complications (IC) caused by bacterial strains often impede
anticancer therapy. The study aimed to retrospectively analyze bacterial IC that could help …