Molecular mechanisms of atopic dermatitis pathogenesis

J Sroka-Tomaszewska, M Trzeciak - International journal of molecular …, 2021 - mdpi.com
Atopic dermatitis is a chronic, non-infectious inflammatory dermatosis. Acharacteristic
feature is persistent itching of the skin. The chronic, relapsing course of the disease …

Environmental risk factors and their role in the management of atopic dermatitis

R Kantor, JI Silverberg - Expert review of clinical immunology, 2017 - Taylor & Francis
Introduction: The etiology of atopic dermatitis (AD) is multifactorial with interaction between
genetics, immune and environmental factors. Areas covered: We review the role of prenatal …

[HTML][HTML] Atopic dermatitis is an IL-13–dominant disease with greater molecular heterogeneity compared to psoriasis

LC Tsoi, E Rodriguez, F Degenhardt, H Baurecht… - Journal of Investigative …, 2019 - Elsevier
Atopic dermatitis (AD) affects up to 20% of children and adults worldwide. To gain a deeper
understanding of the pathophysiology of AD, we conducted a large-scale transcriptomic …

Deciphering the complexities of atopic dermatitis: shifting paradigms in treatment approaches

DYM Leung, E Guttman-Yassky - Journal of Allergy and Clinical …, 2014 - Elsevier
Atopic dermatitis (AD) is the most common chronic inflammatory skin disease. It often
precedes the development of food allergy and asthma. Recent insights into AD reveal …

Genetic and epigenetic studies of atopic dermatitis

L Bin, DYM Leung - Allergy, Asthma & Clinical Immunology, 2016 - Springer
Background Atopic dermatitis (AD) is a chronic inflammatory disease caused by the complex
interaction of genetic, immune and environmental factors. There have many recent …

Epigenetics and allergy: from basic mechanisms to clinical applications

DP Potaczek, H Harb, S Michel, BA Alhamwe… - …, 2017 - Taylor & Francis
Allergic diseases are on the rise in the Western world and well-known allergy-protecting and-
driving factors such as microbial and dietary exposure, pollution and smoking mediate their …

Pathogenesis of atopic dermatitis

W Peng, N Novak - Clinical & Experimental Allergy, 2015 - Wiley Online Library
Atopic dermatitis (AD) is the most common allergic inflammatory skin disease. Interactions of
genetic, environmental and immunological factors result in the initiation and progress of AD …

Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes

J Schmitt, K Schwarz, H Baurecht, M Hotze… - Journal of Allergy and …, 2016 - Elsevier
Background Atopic dermatitis (AD) is characterized by epidermal barrier failure and immune-
mediated inflammation. Evidence on AD as a potential risk factor for inflammatory …

The genetics and epigenetics of atopic dermatitis—filaggrin and other polymorphisms

Y Liang, C Chang, Q Lu - Clinical reviews in allergy & immunology, 2016 - Springer
Atopic dermatitis (AD) is a chronic inflammatory skin disease caused by a combination of
genetic and environmental factors. Genetic evidences depict a complex network comprising …

The translational revolution in atopic dermatitis: the paradigm shift from pathogenesis to treatment

P Facheris, J Jeffery, E Del Duca… - Cellular & Molecular …, 2023 - nature.com
Atopic dermatitis (AD) is the most common inflammatory skin disease, and it is considered a
complex and heterogeneous condition. Different phenotypes of AD, defined according to the …