Moxidectin: an oral treatment for human onchocerciasis
Introduction Moxidectin is a milbemycin endectocide recently approved for the treatment of
human onchocerciasis. Onchocerciasis, earmarked for elimination of transmission, is a …
human onchocerciasis. Onchocerciasis, earmarked for elimination of transmission, is a …
Onchocerciasis elimination: progress and challenges
T Lakwo, D Oguttu, T Ukety, R Post… - Research and Reports …, 2020 - Taylor & Francis
Onchocerciasis is a parasitic infection caused by the filarial nematode Onchocerca volvulus
and transmitted through the bites of black flies of the genus Similium that breed in rivers and …
and transmitted through the bites of black flies of the genus Similium that breed in rivers and …
Alternative treatment strategies to accelerate the elimination of onchocerciasis
M Boussinesq, G Fobi, AC Kuesel - International health, 2018 - academic.oup.com
The use of alternative (or complementary) treatment strategies (ATSs) ie differing from
annual community-directed treatment with ivermectin (CDTI) is required in some African foci …
annual community-directed treatment with ivermectin (CDTI) is required in some African foci …
Reaching the last mile: main challenges relating to and recommendations to accelerate onchocerciasis elimination in Africa
G Gebrezgabiher, Z Mekonnen… - Infectious diseases of …, 2019 - mednexus.org
Background: Onchocerciasis (river blindness), caused by the filarial worm species
Onchocerca volvulus, is a serious vector-borne neglected tropical disease (NTD) of public …
Onchocerca volvulus, is a serious vector-borne neglected tropical disease (NTD) of public …
[HTML][HTML] Research for new drugs for elimination of onchocerciasis in Africa
AC Kuesel - International Journal for Parasitology: Drugs and Drug …, 2016 - Elsevier
Onchocerciasis is a parasitic, vector borne disease caused by the filarial nematode
Onchocerca volvulus. More than 99% of the population at risk of infection live in Africa …
Onchocerca volvulus. More than 99% of the population at risk of infection live in Africa …
[HTML][HTML] Genomic epidemiology in filarial nematodes: transforming the basis for elimination program decisions
Onchocerciasis and lymphatic filariasis are targeted for elimination, primarily using mass
drug administration at the country and community levels. Elimination of transmission is the …
drug administration at the country and community levels. Elimination of transmission is the …
[HTML][HTML] Genome-based tools for onchocerciasis elimination: Utility of the mitochondrial genome for delineating Onchocerca volvulus transmission zones
National programs in Africa have expanded their objectives from control of onchocerciasis
(river blindness) as a public health problem to elimination of parasite transmission …
(river blindness) as a public health problem to elimination of parasite transmission …
[HTML][HTML] Effect of a single dose of 8 mg moxidectin or 150 μg/kg ivermectin on O. volvulus skin microfilariae in a randomized trial: Differences between areas in the …
D Bakajika, EM Kanza, NO Opoku… - PLoS Neglected …, 2022 - journals.plos.org
Background Our study in CDTI-naïve areas in Nord Kivu and Ituri (Democratic Republic of
the Congo, DRC), Lofa County (Liberia) and Nkwanta district (Ghana) showed that a single …
the Congo, DRC), Lofa County (Liberia) and Nkwanta district (Ghana) showed that a single …
[HTML][HTML] Pharmacokinetics of oral moxidectin in individuals with Onchocerca volvulus infection
B Tan, N Opoku, SK Attah, K Awadzi… - PLOS Neglected …, 2022 - journals.plos.org
Background Onchocerciasis (“river blindness”), is a neglected tropical disease caused by
the filarial nematode Onchocerca volvulus and transmitted to humans through repeated …
the filarial nematode Onchocerca volvulus and transmitted to humans through repeated …
Prevalence, risk factors, challenges, and the currently available diagnostic tools for the determination of helminths infections in human
Soil transmitted helminthes (STH) are among the major public health issues in tropical and
sub-tropical countries infecting more than 2 billion humans worldwide. STH causes …
sub-tropical countries infecting more than 2 billion humans worldwide. STH causes …