Extracellular vesicles (EVs) have emerged as a ubiquitous mechanism for transferring
information between cells and organisms across all three kingdoms of life. In addition to their …

Malaria is a mosquito-borne disease caused by protozoan parasites of the genus
Plasmodium. Despite significant declines in malaria-attributable morbidity and mortality over …

Malaria-specific antibody responses are short lived in children, leaving them susceptible to
repeated bouts of febrile malaria. The cellular and molecular mechanisms underlying this …

Malaria causes approximately 212 million cases and 429 thousand deaths annually.
Plasmodium falciparum is responsible for the vast majority of deaths (99%) than others. The …

Mosquito-borne diseases are causing a substantial burden of mortality, morbidity and
economic loss in many parts of the world, despite current control efforts, and new …

Over the past six decades, the drug resistance of Plasmodium falciparum has become an
issue of utmost concern. Despite the remarkable progress that has been made in recent …

Investigation of the diversity of malaria parasite antigens can help prioritize and validate
them as vaccine candidates and identify the most common variants for inclusion in vaccine …

Malaria is a global infectious disease that remains a leading cause of morbidity and mortality
in the developing world. Multiple environmental and host and parasite factors govern the …

After more than 50 years of intensive research and development, only one malaria vaccine
candidate,“RTS, S,” has progressed to Phase 3 clinical trials. Despite only partial efficacy …

Type I IFNs are known to inhibit viral replication and mediate protection against viral
infection. However, recent studies revealed that these cytokines play a broader and more …