Conception, synthèse et évaluation des dérivés d'aminobenzosubérone comme inhibiteurs potentiels des aminopeptidases de la famille M1

M Al-Masri - 2017 - theses.hal.science
Les aminopeptidases de la famille M1 sont des protéases qui catalysent l'hydrolyse d'une
liaison peptidique en position N-terminale. Ce sont des métalloprotéases avec un ion zinc …

[PDF][PDF] The antigen presenting potential of V 9Vδβ T-cells during Plasmodium falciparum blood-stage infection.

J Howard, S Loizon, CJ Tyler, D Duluc, B Moser… - 2017 - scholar.archive.org
V 9Vδβ T-cells with APC-like phenotype can be found in vivo in P. falciparum-infected
patients. V 9Vδβ T-cells stimulated in vitro with P. falciparum-infected red blood cell acquire …

An investigation of the impact of parasitic worm infection on the immunogenicity of candidate HIV vaccines

GA Dzhivhuho - 2017 - open.uct.ac.za
Abstract Development of effective and affordable HIV vaccines is one of the best and cost-
effective strategies for controlling the HIV epidemic and a top priority in endemic areas …

Role of the Histamine Releasing Factor (HRF) in Plasmodium parasite transmission and disease pathogenesis

C Demarta-Gatsi - 2016 - theses.hal.science
Recent findings have raised the hypothesis that clinical susceptibility to malaria may be
related to allergy-type response. In human infection with P. falciparum, as well as in murine …

[PDF][PDF] The role of monocytes in the development of natural immunity to Plasmodium infection

AM Baccarella - 2016 - escholarship.org
Malaria, caused by parasites of the genus Plasmodium, is a leading cause of infectious
morbidity and mortality worldwide (WHO Global Malaria Programme, 2012). Malaria …

Conception, synthèse et évaluation biologique d'inhibiteurs de PfA-M17, potentielle cible antipaludéenne

B Chaillou - 2015 - theses.hal.science
Le paludisme, maladie infectieuse due à des parasites du genre Plasmodium, reste mortel
et préoccupant dans les régions intertropicales d'Afrique, d'Asie et d'Amérique. Les …

Engineered tools for studying the malaria parasite Plasmodium falciparum

BBA Wall - 2015 - dspace.mit.edu
New techniques to both prevent and treat the disease malaria are necessary. To develop
these novel strategies, innovative tools must be designed to study the basic biology within …

Plasmodium falciparum circumsporozoite protein: target of cellular immunity against traversed hepatocytes and naturally induced memory responses

SA Trop - 2015 - jscholarship.library.jhu.edu
Vaccines against exoerythrocytic stages of malaria remain ineffective in the face of limited
knowledge on processing and presentation of parasite antigens in the liver. Here, we show …

DEFINING IMMUNE CORRELATES OF MALARIA USING PLASMODIUM YOELII MOUSE MODELS

CWAN NI - 2015 - scholarbank.nus.edu.sg
PROTECTIVE TARGETS AND THE OPTIMUM MEASURES OF ANTIBODY IMMUNITY IN
MALARIA ARE STILL CURRENTLY UNCLEAR TO RESEARCHERS. WE DESIGNED AND …

[PDF][PDF] Evaluation of chimeric virus-like particles, capsomeres and bacterial minicells as vaccine delivery platforms

D Pattinson - 2014 - core.ac.uk
Malaria is a major public health problem, with an estimated 207 million cases and 627,000
deaths each year as well as associated socio-economic costs. Considerable inroads have …