[HTML][HTML] CRISPR-Cas systems: Overview, innovations and applications in human disease research and gene therapy

Y Xu, Z Li - Computational and structural biotechnology journal, 2020 - Elsevier
Genome editing is the modification of genomic DNA at a specific target site in a wide variety
of cell types and organisms, including insertion, deletion and replacement of DNA, resulting …

[HTML][HTML] Human papillomavirus in cancer: Infection, disease transmission, and progress in vaccines

AAA Oyouni - Journal of infection and public health, 2023 - Elsevier
Human papillomaviruses (HPVs) infect epithelial cells of human beings, and their replication
cycle is associated with epithelial differentiation. More than 200 genotypes of HPVs were …

ICTV Virus Taxonomy Profile: Papillomaviridae

K Van Doorslaer, Z Chen… - Journal of General …, 2018 - microbiologyresearch.org
The Papillomaviridae is a family of small, non-enveloped viruses with double-stranded DNA
genomes of 5 748 to 8 607 bp. Their classification is based on pairwise nucleotide …

Oral manifestations of human papillomavirus infections

S Syrjänen - European journal of oral sciences, 2018 - Wiley Online Library
Papillomaviruses are one of the oldest viruses known, dating back 330 million years. During
this long evolution, human papillomaviruses (HPV) have developed into hijackers of human …

Advances in HPV‐associated tumor management: therapeutic strategies and emerging insights

X Gong, H Chi, Z Xia, G Yang… - Journal of Medical …, 2023 - Wiley Online Library
With the rapid increase in the incidence of cervical cancer, anal cancer and other cancers,
human papillomavirus (HPV) infection has become a growing concern. Persistent infection …

[HTML][HTML] Role of immunity and vaginal microbiome in clearance and persistence of human papillomavirus infection

L Ntuli, A Mtshali, G Mzobe, LJP Liebenberg… - Frontiers in cellular …, 2022 - frontiersin.org
Cervical cancer disproportionately affects women of reproductive age, with 80% of cases
occurring in low-and middle-income countries. Persistent infection with high-risk human …

Hallmarks of HPV carcinogenesis: The role of E6, E7 and E5 oncoproteins in cellular malignancy

D Estêvão, NR Costa, RMG da Costa… - Biochimica et Biophysica …, 2019 - Elsevier
Human papillomavirus (HPV) is the most common sexually transmitted infectious agent
worldwide, being also responsible for 5% of all human cancers. The integration and …

Biology of HPV mediated carcinogenesis and tumor progression

PF Cosper, S Bradley, Q Luo, RJ Kimple - Seminars in radiation oncology, 2021 - Elsevier
Human papillomavirus (HPV) is a ubiquitous DNA virus that infects squamous epithelia.
Though HPV only encodes 8 genes, it is capable of causing cellular transformation and …

[HTML][HTML] Tracking HPV infection, associated cancer development, and recent treatment efforts—a comprehensive review

S Malik, R Sah, K Muhammad, Y Waheed - Vaccines, 2023 - mdpi.com
Human papillomaviruses (HPVs) are high-risk causative factors for HPV infection. This
infection does not come alone; it is often seen with co-infection with other viruses and acts …

[HTML][HTML] Update on human papilloma virus - part I: epidemiology, pathogenesis, and clinical spectrum,,

GM Magalhães, ÉC Vieira, LC Garcia… - Anais Brasileiros de …, 2021 - SciELO Brasil
Infection with human papilloma virus (HPV) is related to a great number of cutaneous and
mucosal manifestations. The spectrum of HPV ranges from inapparent infections, through …