Butyrate Inhibits Osteoclast Activity In Vitro and Regulates Systemic Inflammation and Bone Healing in a Murine Osteotomy Model Compared to Antibiotic‐Treated …

A Wallimann, W Magrath, B Pugliese… - Mediators of …, 2021 - Wiley Online Library
Short‐chain fatty acids (SCFAs) produced by the gut microbiota have previously been
demonstrated to play a role in numerous chronic inflammatory diseases and to be key …

[HTML][HTML] Contribution of IL-1β, 6 and TNF-α to the form of post-traumatic osteoarthritis induced by “idealized” anterior cruciate ligament reconstruction in a porcine …

P Han, L Wei, Z Duan, Z Zhang, T Chen, J Lu… - International …, 2018 - Elsevier
Background It has been noted that anterior cruciate ligament (ACL) injury-induced cartilage
degeneration is the key risk factor for post-traumatic osteoarthritis (PTOA). However, whether …

Advances in bone turnover markers

L Di Medio, ML Brandi - Advances in Clinical Chemistry, 2021 - Elsevier
Bone fragility fractures remain an important worldwide health and economic problem due to
increased morbidity and mortality. The current methods for predicting fractures are largely …

Development and use of biochemical markers in osteoarthritis: current update

AC Bay-Jensen, CS Thudium… - Current opinion in …, 2018 - journals.lww.com
Osteoarthritis is the most common form of joint disease. This presents the osteoarthritis
research community and pharmaceutical companies developing disease-modifying …

The serum level of Dickkopf-1 in patients with rheumatoid arthritis: a systematic review and meta-analysis

Y Ma, X Zhang, M Wang, Q Xia, J Yang, M Wu… - International …, 2018 - Elsevier
Abstract Objective Dickkopf-1 (DKK-1) is an endogenous inhibitor of canonical Wnt pathway
that was implicated in the pathogenesis of rheumatoid arthritis (RA), but the serum levels of …

[HTML][HTML] Therapeutic potential of Coptis chinensis for arthritis with underlying mechanisms

M Li, F Tian, J Guo, X Li, L Ma, M Jiang… - Frontiers in …, 2023 - frontiersin.org
Arthritis is a common degenerative disease of joints, which has become a public health
problem affecting human health, but its pathogenesis is complex and cannot be eradicated …

[HTML][HTML] The Role of Tocotrienol in Arthritis Management—A Scoping Review of Literature

HS Tejpal Singh, AA Aminuddin, KL Pang, SO Ekeuku… - Pharmaceuticals, 2023 - mdpi.com
Arthritis is a cluster of diseases impacting joint health and causing immobility and morbidity
in the elderly. Among the various forms of arthritis, osteoarthritis (OA) and rheumatoid …

[HTML][HTML] Study on the molecular mechanism of Guizhi Jia Shaoyao decoction for the treatment of knee osteoarthritis by utilizing network pharmacology and molecular …

P Deng, H Liang, K Xie, J Han, F Huang… - Allergologia Et …, 2021 - all-imm.com
Background and objective Guizhi Jia Shaoyao decoction (GSD) is widely used in the clinical
treatment of knee osteoarthritis (KOA). However, the underlying molecular mechanisms …

[HTML][HTML] Substance P and alpha-calcitonin gene-related peptide differentially affect human osteoarthritic and healthy chondrocytes

S Stöckl, A Eitner, RJ Bauer, M König… - Frontiers in …, 2021 - frontiersin.org
Osteoarthritis (OA) is a degenerative joint disease that not only causes cartilage loss but
also structural damage in all joint tissues. Joints are innervated by alpha-calcitonin gene …

[HTML][HTML] Evaluation of circulating levels of Interleukin-10 and Interleukin-16 and dietary inflammatory index in Lebanese knee osteoarthritis patients

Z El-Ali, G El-Kassas, FM Ziade, N Shivappa, JR Hébert… - Heliyon, 2021 - cell.com
Objectives To investigate plasma concentrations of Interleukin-16 (IL-16) and Interleukin-10
(IL-10) in Lebanese knee osteoarthritis (KOA) patients and to examine the association …