Chloroquine and sulfadoxine–pyrimethamine resistance in Sub-Saharan Africa—A review
Malaria is a great concern for global health and accounts for a large amount of morbidity and
mortality, particularly in Africa, with sub-Saharan Africa carrying the greatest burden of the …
mortality, particularly in Africa, with sub-Saharan Africa carrying the greatest burden of the …
Geographical spread and structural basis of sulfadoxine-pyrimethamine drug-resistant malaria parasites
The global spread of sulfadoxine (Sdx, S) and pyrimethamine (Pyr, P) resistance is attributed
to increasing number of mutations in DHPS and DHFR enzymes encoded by malaria …
to increasing number of mutations in DHPS and DHFR enzymes encoded by malaria …
Prevalence of Plasmodium falciparum haplotypes associated with resistance to sulfadoxine–pyrimethamine and amodiaquine before and after upscaling of seasonal …
KB Beshir, J Muwanguzi, J Nader… - The Lancet Infectious …, 2023 - thelancet.com
Background Seasonal malaria chemoprevention is used in 13 countries in the Sahel region
of Africa to prevent malaria in children younger than 5 years. Resistance of Plasmodium …
of Africa to prevent malaria in children younger than 5 years. Resistance of Plasmodium …
Spatiotemporal spread of Plasmodium falciparum mutations for resistance to sulfadoxine-pyrimethamine across Africa, 1990–2020
JA Flegg, GS Humphreys, B Montanez… - PLOS Computational …, 2022 - journals.plos.org
Background Sulfadoxine-pyrimethamine (SP) is recommended in Africa in several
antimalarial preventive regimens including Intermittent Preventive Treatment in pregnant …
antimalarial preventive regimens including Intermittent Preventive Treatment in pregnant …
High prevalence of Pfdhfr–Pfdhps quadruple mutations associated with sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates from Bioko Island …
T Jiang, J Chen, H Fu, K Wu, Y Yao, JUM Eyi… - Malaria journal, 2019 - Springer
Background Sulfadoxine–pyrimethamine (SP) is recommended for intermittent preventive
treatment of malaria in Africa. However, increasing SP resistance (SPR) affects the …
treatment of malaria in Africa. However, increasing SP resistance (SPR) affects the …
Effect of three years' seasonal malaria chemoprevention on molecular markers of resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine and …
Background In 2012, seasonal malaria chemoprevention (SMC) was recommended as
policy for malaria control by the World Health Organization (WHO) in areas of highly …
policy for malaria control by the World Health Organization (WHO) in areas of highly …
Markers of sulfadoxine–pyrimethamine resistance in Eastern Democratic Republic of Congo; implications for malaria chemoprevention
M van Lenthe, R van Der Meulen, M Lassovski… - Malaria journal, 2019 - Springer
Background Sulfadoxine–pyrimethamine (SP) is a cornerstone of malaria chemoprophylaxis
and is considered for programmes in the Democratic Republic of Congo (DRC). However …
and is considered for programmes in the Democratic Republic of Congo (DRC). However …
Effect of seasonal malaria chemoprevention in children between 5 and 9 years old in Kita and Bafoulabe districts, Mali
SI Diawara, D Konaté, K Kayentao, J Mihigo… - Parasite epidemiology …, 2022 - Elsevier
Background Seasonal malaria chemoprevention (SMC) has been widely expanded in Mali
since its recommendation by the the World Health Organization in 2012. SMC guidelines …
since its recommendation by the the World Health Organization in 2012. SMC guidelines …
The prevalence of molecular markers of resistance to sulfadoxine-pyrimethamine among pregnant women at first antenatal clinic attendance and delivery in the forest …
Intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine (IPTp-
SP) is used to prevent malaria and associated unfavorable maternal and foetal outcomes in …
SP) is used to prevent malaria and associated unfavorable maternal and foetal outcomes in …
An online mapping database of molecular markers of drug resistance in Plasmodium falciparum: the ACT Partner Drug Molecular Surveyor
SD Otienoburu, I Suay, S Garcia, NV Thomas… - Malaria journal, 2019 - Springer
Background Prior to this project, only a handful of online visualizations existed for exploring
the published literature on molecular markers of antimalarial drug resistance, and none …
the published literature on molecular markers of antimalarial drug resistance, and none …