[HTML][HTML] Cancer immunotherapy update: FDA-approved checkpoint inhibitors and companion diagnostics

JD Twomey, B Zhang - The AAPS journal, 2021 - Springer
Immune checkpoint inhibitors (ICIs) are considered a new standard-of-care across many
cancer indications. This review provides an update on ICIs approved by the Food and Drug …

[HTML][HTML] Therapeutic progress and challenges for triple negative breast cancer: Targeted therapy and immunotherapy

R Yang, Y Li, H Wang, T Qin, X Yin, X Ma - Molecular biomedicine, 2022 - Springer
Triple negative breast cancer (TNBC) is a subtype of breast cancer, with estrogen receptor,
human epidermal growth factor receptor 2 and progesterone receptor negative. TNBC is …

[HTML][HTML] Chemoresistance in breast cancer: PI3K/Akt pathway inhibitors vs the current chemotherapy

PJ Kaboli, S Imani, M Jomhori… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Breast cancer is the most prevalent type of cancer among women. Several types of drugs,
targeting the specific proteins expressed on the breast cancer cell surface (such as receptor …

[HTML][HTML] An angiogenesis-related lncRNA signature predicts the immune microenvironment and prognosis of breast cancer

YW Wang, C Liu, YD Chen, B Yang, X Chen… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Both angiogenesis and lncRNAs play crucial roles in the development and progression of
breast cancer. Considering the unknown association of angiogenesis and lncRNAs in breast …

Current treatment landscape and emerging therapies for metastatic triple-negative breast cancer.

NG Adel - American journal of managed care, 2021 - search.ebscohost.com
A lack of therapeutically targetable molecular alterations and its aggressive nature make
triple-negative breast cancer [TNBC] a challenging disease. Chemotherapy is standard of …

Tissue factor overexpression in triple-negative breast cancer promotes immune evasion by impeding T-cell infiltration and effector function

Z Ren, Y Xue, L Liu, X Zhang, J Pei, Y Zhang, Y Wang… - Cancer Letters, 2023 - Elsevier
Triple-negative breast cancer (TNBC) remains a most deadly human malignancy with limited
response to chemotherapy, targeted therapy and immunotherapy. Tumor …

Trilaciclib prior to gemcitabine plus carboplatin for metastatic triple-negative breast cancer: phase III PRESERVE 2

S Goel, AR Tan, HS Rugo, P Aftimos, Z Andrić… - Future …, 2022 - Taylor & Francis
Triple-negative breast cancer (TNBC) is an aggressive malignancy for which cytotoxic
chemotherapy remains the backbone of treatment. Trilaciclib is an intravenous cyclin …

[HTML][HTML] Immune classification and immune landscape analysis of triple-negative breast cancer

S Hu, X Qu, Y Jiao, J Hu, B Wang - Frontiers in Genetics, 2021 - frontiersin.org
Background: To classify triple-negative breast cancer (TNBC) immunotyping using the public
database, analyze the differences between subtypes in terms of clinical characteristics and …

Ex Vivo Evaluation of Combination Immunotherapy Using Tumor‐Microenvironment‐on‐Chip

HY Mu, CM Lin, LA Chu, YH Lin, J Li… - Advanced …, 2024 - Wiley Online Library
Combination immunotherapy has emerged as a promising strategy to address the
challenges associated with immune checkpoint inhibitor (ICI) therapy in breast cancer. The …

[HTML][HTML] Clinical outcomes associated with monotherapy and combination therapy of immune checkpoint inhibitors as first-line treatment for advanced hepatocellular …

H Zou, Q Lei, X Yan, Y Lai, COL Ung, H Hu - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is one of the most malignant tumors.
Immune checkpoint inhibitors (ICIs)-based therapy has recently been demonstrated to …