Autism spectrum disorders and the gastrointestinal tract: insights into mechanisms and clinical relevance

LY Hung, KG Margolis - Nature Reviews Gastroenterology & …, 2024 - nature.com
Autism spectrum disorders (ASDs) are recognized as central neurodevelopmental disorders
diagnosed by impairments in social interactions, communication and repetitive behaviours …

Repetitive restricted behaviors in autism spectrum disorder: From mechanism to development of therapeutics

J Tian, X Gao, L Yang - Frontiers in neuroscience, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by deficits in social communication, social interaction, and repetitive restricted behaviors …

TAU ablation in excitatory neurons and postnatal TAU knockdown reduce epilepsy, SUDEP, and autism behaviors in a Dravet syndrome model

E Shao, CW Chang, Z Li, X Yu, K Ho, M Zhang… - Science translational …, 2022 - science.org
Intracellular accumulation of TAU aggregates is a hallmark of several neurodegenerative
diseases. However, global genetic reduction of TAU is beneficial also in models of other …

[HTML][HTML] Hydroalcoholic extract of Passiflora incarnata improves the autistic-like behavior and neuronal damage in a valproic acid-induced rat model of autism

F Amini, H Amini-Khoei, S Haratizadeh… - Journal of Traditional …, 2023 - Elsevier
Experimental autism in rodents can be caused by prenatal valproic acid (VPA) exposure.
Some diseases, such as attention-deficit hyperactivity disorder (ADHD), insomnia, opiate …

A recurrent SHANK1 mutation implicated in autism spectrum disorder causes autistic-like core behaviors in mice via downregulation of mGluR1-IP3R1-calcium …

Y Qin, Y Du, L Chen, Y Liu, W Xu, Y Liu, Y Li… - Molecular …, 2022 - nature.com
The genetic etiology and underlying mechanism of autism spectrum disorder (ASD) remain
elusive. SHANK family genes (SHANK1/2/3) are well known ASD-related genes. However …

Effectiveness of physical activity interventions for core symptoms of autism spectrum disorder: A systematic review and meta‐analysis

S Wang, D Chen, Y Yang, L Zhu, X Xiong… - Autism …, 2023 - Wiley Online Library
In this paper, systematic review and meta‐analysis were used to demonstrate the
effectiveness of physical activity intervention on core symptoms of autism spectrum disorder …

Altered motor learning and coordination in mouse models of autism spectrum disorder

KR Cording, HS Bateup - Frontiers in cellular neuroscience, 2023 - frontiersin.org
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with increasing
prevalence. Over 1,000 risk genes have now been implicated in ASD, suggesting diverse …

Recent developments in autism genetic research: A scientometric review from 2018 to 2022

M Lim, A Carollo, D Dimitriou, G Esposito - Genes, 2022 - mdpi.com
Genetic research in Autism Spectrum Disorder (ASD) has progressed tremendously in
recent decades. Dozens of genetic loci and hundreds of alterations in the genetic sequence …

Sex and age differences in social and cognitive function in offspring exposed to late gestational hypoxia

S Mabry, EN Wilson, JL Bradshaw, JJ Gardner… - Biology of sex …, 2023 - Springer
Background Gestational sleep apnea is a hypoxic sleep disorder that affects 8–26% of
pregnancies and increases the risk for central nervous system dysfunction in offspring …

The emerging complexity of molecular pathways implicated in mouse self-grooming behavior

AN Ikrin, AM Moskalenko, RR Mukhamadeev… - Progress in Neuro …, 2023 - Elsevier
Rodent self-grooming is an important complex behavior, and its deficits are translationally
relevant to a wide range of neuropsychiatric disorders. Here, we analyzed a comprehensive …