The heterocellular heart: identities, interactions, and implications for cardiology
The heterocellular nature of the heart has been receiving increasing attention in recent
years. In addition to cardiomyocytes as the prototypical cell type of the heart, non-myocytes …
years. In addition to cardiomyocytes as the prototypical cell type of the heart, non-myocytes …
[HTML][HTML] Cardiac Fibrosis in heart failure: Focus on non-invasive diagnosis and emerging therapeutic strategies
S Ravassa, B López, TA Treibel, G San José… - Molecular Aspects of …, 2023 - Elsevier
Heart failure is a leading cause of mortality and hospitalization worldwide. Cardiac fibrosis,
resulting from the excessive deposition of collagen fibers, is a common feature across the …
resulting from the excessive deposition of collagen fibers, is a common feature across the …
Modelling the pathology and treatment of cardiac fibrosis in vascularised atrial and ventricular cardiac microtissues
JS Reyat, A di Maio, B Grygielska, J Pike… - Frontiers in …, 2023 - frontiersin.org
Introduction Recent advances in human cardiac 3D approaches have yielded progressively
more complex and physiologically relevant culture systems. However, their application in the …
more complex and physiologically relevant culture systems. However, their application in the …
A Biomimetic Cardiac Fibrosis-on-a-Chip as a Visible Disease Model for Evaluating Mesenchymal Stem Cell-Derived Exosome Therapy
Y Shang, L Sun, J Gan, D Xu, Y Zhao, L Sun - ACS nano, 2023 - ACS Publications
Cardiac fibrosis acts as a serious worldwide health issue due to its prevalence in numerous
forms of cardiac disease and its essential link to cardiac failure. Considering the efficiency of …
forms of cardiac disease and its essential link to cardiac failure. Considering the efficiency of …
Macrophages in cardiovascular diseases: molecular mechanisms and therapeutic targets
R Chen, H Zhang, B Tang, Y Luo, Y Yang… - … and Targeted Therapy, 2024 - nature.com
The immune response holds a pivotal role in cardiovascular disease development. As
multifunctional cells of the innate immune system, macrophages play an essential role in …
multifunctional cells of the innate immune system, macrophages play an essential role in …
Anisotropically Deforming Sandwich-Type Self-Oscillating Gels: A Hierarchical Model Platform of Cardiac Tissue
WS Lee, T Enomoto, A Mizutani Akimoto… - Chemistry of …, 2024 - ACS Publications
Here, we present sandwich-type self-oscillating gels as a potential model for exploring the
cardiac hierarchy and derived emergent properties. The sandwich-type self-oscillating gels …
cardiac hierarchy and derived emergent properties. The sandwich-type self-oscillating gels …
Intercellular pathways of cancer treatment-related cardiotoxicity and their therapeutic implications: The paradigm of radiotherapy
S Logotheti, A Pavlopoulou, HK Rudsari… - Pharmacology & …, 2024 - Elsevier
Advances in cancer therapeutics have improved patient survival rates. However, cancer
survivors may suffer from adverse events either at the time of therapy or later in life …
survivors may suffer from adverse events either at the time of therapy or later in life …
Cardiovascular Organoids/3D Models Review Series: An Introduction
C St. Hilaire - Circulation research, 2023 - Am Heart Assoc
Even with the vast amount of research focused on uncovering the etiology and molecular
mechanisms that drive the progression of cardiovascular disease, along with concerted …
mechanisms that drive the progression of cardiovascular disease, along with concerted …
Advances in the Generation of Constructed Cardiac Tissue Derived from Induced Pluripotent Stem Cells for Disease Modeling and Therapeutic Discovery
The human heart lacks significant regenerative capacity; thus, the solution to heart failure
(HF) remains organ donation, requiring surgery and immunosuppression. The demand for …
(HF) remains organ donation, requiring surgery and immunosuppression. The demand for …
NAVIGATING THE VASCULAR FRONTIER: EXPLORING QUERCETIN-BASED DRUG DELIVERY STRATEGIES IN CARDIOVASCULAR THERAPY
This comprehensive review delves into the utilization of quercetin-based drug delivery
systems in cardiovascular therapy, with a primary focus on various nanoparticle strategies …
systems in cardiovascular therapy, with a primary focus on various nanoparticle strategies …