Mosquito gene targeted RNAi studies for vector control

M Yadav, N Dahiya, N Sehrawat - Functional & Integrative Genomics, 2023 - Springer
Vector-borne diseases are serious public health concern. Mosquito is one of the major
vectors responsible for the transmission of a number of diseases like malaria, Zika …

ZIKV: Epidemiology, infection mechanism and current therapeutics

N Dahiya, M Yadav, H Singh, R Jakhar… - Frontiers in Tropical …, 2023 - frontiersin.org
The Zika virus (ZIKV) is a vector-borne flavivirus that has been detected in 87 countries
worldwide. Outbreaks of ZIKV infection have been reported from various places around the …

Zika Virus NS1 Suppresses VE-Cadherin and Claudin-5 via hsa-miR-101-3p in human brain microvascular endothelial cells

U Bhardwaj, SK Singh - Molecular neurobiology, 2021 - Springer
Zika virus (ZIKV) is a neurotropic virus that causes microcephaly in newborns and Guillain-
Barré syndrome (GBS) in adults. ZIKV is known to transmigrate through the blood–brain …

Fragment-based design of α-cyanoacrylates and α-cyanoacrylamides targeting Dengue and Zika NS2B/NS3 proteases

GG Vilela, WF dos Santos Silva… - New Journal of …, 2022 - pubs.rsc.org
Viruses belonging to the Flaviviridae family account for millions of cases of infections
worldwide, mainly Dengue (DENV) and Zika (ZIKV) viruses. Both mosquito-borne …

Efficient gene transfer to kidney using a lentiviral vector pseudotyped with zika virus envelope glycoprotein

J Liu, Y Mao, Q Li, Z Qiu, J Li, X Li, W Liang… - Human Gene …, 2022 - liebertpub.com
Gene therapy's entrance into clinical settings has made it an ever more attractive field of
study for various diseases. However, relatively little progress has been made in targeting …

[HTML][HTML] Zika virus replication on endothelial cells and invasion into the central nervous system by inhibiting interferon β translation

K Wang, S Zou, H Chen, D Higazy, X Gao, Y Zhang… - Virology, 2023 - Elsevier
The blood-brain barrier (BBB) is one of the tightest physical barriers to prevent pathogens
from invading the central nervous system (CNS). However, the mechanism by which Zika …

Portable all-in-one microfluidic system for CRISPR‒Cas13a-based fully integrated multiplexed nucleic acid detection

Y Zhang, Y Guo, G Liu, S Zhou, R Su, Q Ma, Y Ge… - Lab on a Chip, 2024 - pubs.rsc.org
Point-of-care testing of “sample in, answer out” is urgently needed for communicable
diseases. Recently, rapid nucleic acid tests for infectious diseases have been developed for …

Zika virus NS1 suppresses VE-cadherin via hsa-miR-29b-3p/DNMT3b/MMP-9 pathway in human brain microvascular endothelial cells

U Bhardwaj, SK Singh - Cellular Signalling, 2023 - Elsevier
Zika virus infection has been reported to cause microcephaly in newborns. ZIKV exploits
various strategies to cross the blood-brain barrier. ZIKV NS1 may compromise the barrier …

Global Prevalence of Zika and Chikungunya Coinfection: A Systematic Review and Meta-Analysis

S Ahmed, S Sultana, S Kundu, SS Alam, T Hossan… - Diseases, 2024 - mdpi.com
Zika virus (ZIKV) and chikungunya virus (CHIKV) are arthropod-borne viruses with
significant pathogenicity, posing a substantial health and economic burden on a global …

Zika Virus: A Neurotropic Warrior against High-Grade Gliomas—Unveiling Its Potential for Oncolytic Virotherapy

MA Calderón-Peláez, SJ Maradei Anaya… - Viruses, 2024 - mdpi.com
Gliomas account for approximately 75–80% of all malignant primary tumors in the central
nervous system (CNS), with glioblastoma multiforme (GBM) considered the deadliest …