Chronic wound healing models

K Flynn, NN Mahmoud, S Sharifi, LJ Gould… - ACS Pharmacology & …, 2023 - ACS Publications
In this paper, we review and analyze the commonly available wound healing models
reported in the literature and discuss their advantages and issues, considering their …

Preclinical study models of psoriasis: State-of-the-art techniques for testing pharmaceutical products in animal and nonanimal models

K Yadav, D Singh, MR Singh, S Minz… - International …, 2023 - Elsevier
Local and systemic treatments exist for psoriasis, but none can do more than control its
symptoms because of its numerous unknown mechanisms. The lack of validated testing …

Advances in zebrafish for diabetes mellitus with wound model

B Lin, J Ma, Y Fang, P Lei, L Wang, L Qu, W Wu, L Jin… - Bioengineering, 2023 - mdpi.com
Diabetic foot ulcers cause great suffering and are costly for the healthcare system. Normal
wound healing involves hemostasis, inflammation, proliferation, and remodeling. However …

Triphenyl phosphate-induced pericardial edema in zebrafish embryos is dependent on the ionic strength of exposure media

J Wiegand, S Avila-Barnard, C Nemarugommula… - Environment …, 2023 - Elsevier
Pericardial edema is commonly observed in zebrafish embryo-based chemical toxicity
screens, and a mechanism underlying edema may be disruption of embryonic …

Anti-Cancer and Anti-Inflammatory Activities of a Short Molecule, PS14 Derived from the Virulent Cellulose Binding Domain of Aphanomyces invadans, on Human …

M Velayutham, P Sarkar, G Sudhakaran, KA Al-Ghanim… - Molecules, 2022 - mdpi.com
In this study, the anti-cancer and anti-inflammatory activities of PS14, a short peptide derived
from the cellulase binding domain of pathogenic fungus, Aphanomyces invadans, have …

Ozonated sunflower oil exerted potent anti-inflammatory activities with enhanced wound healing and tissue regeneration abilities against acute toxicity of …

KH Cho, JE Kim, A Bahuguna, DJ Kang - Antioxidants, 2023 - mdpi.com
Ozonated sunflower oil (OSO) is an established therapeutic agent and nutraceutical
harboring various therapeutic values, including antiallergic, derma-protective, and broad …

Do curdlan hydrogels improved with bioactive compounds from hop exhibit beneficial properties for skin wound healing?

A Nurzynska, K Klimek, A Michalak… - International Journal of …, 2023 - mdpi.com
Chronic wounds, among others, are mainly characterized by prolonged inflammation
associated with the overproduction of reactive oxygen species and pro-inflammatory …

PS9, derived from an aquatic Fungus virulent protein, glycosyl hydrolase, arrests MCF-7 proliferation by regulating intracellular reactive oxygen species and apoptotic …

M Velayutham, P Sarkar, KM Karuppiah… - ACS …, 2023 - ACS Publications
One of the most common diseases in women is breast cancer, which has the highest death
globally. Surgery, chemotherapy, hormone treatments, and radiation are the current …

The Zebrafish model in dermatology: an update for clinicians

I Russo, E Sartor, L Fagotto, A Colombo, N Tiso… - Discover Oncology, 2022 - Springer
Recently, the zebrafish has been established as one of the most important model organisms
for medical research. Several studies have proved that there is a high level of similarity …

Plants as modulators of melanogenesis: Role of extracts, pure compounds and patented compositions in therapy of pigmentation disorders

A Merecz-Sadowska, P Sitarek, J Stelmach… - International Journal of …, 2022 - mdpi.com
The kingdom of plants as a “green biofabric” of valuable bioactive molecules has long been
used in many ailments. Currently, extracts and pure compounds of plant origin are used to …