[HTML][HTML] Aqueous outflow-A continuum from trabecular meshwork to episcleral veins
T Carreon, E van der Merwe, RL Fellman… - Progress in retinal and …, 2017 - Elsevier
In glaucoma, lowered intraocular pressure (IOP) confers neuroprotection. Elevated IOP
characterizes glaucoma and arises from impaired aqueous humor (AH) outflow. Increased …
characterizes glaucoma and arises from impaired aqueous humor (AH) outflow. Increased …
[HTML][HTML] Normal and glaucomatous outflow regulation
Glaucoma remains only partially understood, particularly at the level of intraocular pressure
(IOP) regulation. Trabecular meshwork (TM) and Schlemm's canal inner wall endothelium …
(IOP) regulation. Trabecular meshwork (TM) and Schlemm's canal inner wall endothelium …
The vital role for nitric oxide in intraocular pressure homeostasis
Catalyzed by endothelial nitric oxide (NO) synthase (eNOS) activity, NO is a gaseous
signaling molecule maintaining endothelial and cardiovascular homeostasis. Principally, NO …
signaling molecule maintaining endothelial and cardiovascular homeostasis. Principally, NO …
[HTML][HTML] Morphological and biomechanical analyses of the human healthy and glaucomatous aqueous outflow pathway: Imaging-to-modeling
Abstract Background and Objective: Intraocular pressure (IOP) is maintained via a dynamic
balance between the production of aqueous humor and its drainage through the trabecular …
balance between the production of aqueous humor and its drainage through the trabecular …
Fluorescein aqueous angiography in live normal human eyes
Purpose: To evaluate aqueous humor outflow (AHO) in intact eyes of live human subjects
during cataract surgery using fluorescein aqueous angiography. Methods: Aqueous …
during cataract surgery using fluorescein aqueous angiography. Methods: Aqueous …
Aqueous angiography in living nonhuman primates shows segmental, pulsatile, and dynamic angiographic aqueous humor outflow
Purpose To evaluate the feasibility of safely performing aqueous angiography in intact eyes
of living nonhuman primates (NHPs) for evaluating aqueous humor outflow and segmental …
of living nonhuman primates (NHPs) for evaluating aqueous humor outflow and segmental …
[HTML][HTML] Aqueous angiography–mediated guidance of trabecular bypass improves angiographic outflow in human enucleated eyes
AS Huang, S Saraswathy, A Dastiridou… - … & visual science, 2016 - jov.arvojournals.org
Purpose: To assess the ability of trabecular micro-bypass stents to improve aqueous humor
outflow (AHO) in regions initially devoid of AHO as assessed by aqueous angiography …
outflow (AHO) in regions initially devoid of AHO as assessed by aqueous angiography …
Structural and functional imaging of aqueous humour outflow: a review
AS Huang, BA Francis… - Clinical & experimental …, 2018 - Wiley Online Library
Maintaining healthy aqueous humour outflow (AHO) is important for intraocular cellular
health and stable vision. Impairment of AHO can lead to increased intraocular pressure …
health and stable vision. Impairment of AHO can lead to increased intraocular pressure …
The outflow pathway: a tissue with morphological and functional unity
SC Saccà, S Gandolfi, A Bagnis… - Journal of cellular …, 2016 - Wiley Online Library
The trabecular meshwork (TM) plays an important role in high‐tension glaucomas. Indeed,
the TM is a true organ, through which the aqueous humor flows from the anterior chamber to …
the TM is a true organ, through which the aqueous humor flows from the anterior chamber to …
[HTML][HTML] Rho kinase inhibitor AR-12286 reverses steroid-induced changes in intraocular pressure, effective filtration areas, and morphology in mouse eyes
R Ren, AA Humphrey, C Kopczynski… - … & Visual Science, 2023 - iovs.arvojournals.org
Purpose: We investigated mechanisms of reduction of intraocular pressure (IOP) by Rho
kinase inhibitor AR-12286 in steroid-induced ocular hypertension (SIOH). Methods …
kinase inhibitor AR-12286 in steroid-induced ocular hypertension (SIOH). Methods …