Alveolar macrophages have been investigated for years by approaches involving
macrophage extraction from the lung by bronchoalveolar lavage, or by cell removal from …

The goals of this study were to characterize the changes in chondroitin sulfate proteoglycans
and hyaluronan in lungs in acute response to gram-negative bacterial infection and to …

In contrast to other organs, the lung completes a significant portion of its development after
term birth. During this stage of alveolarization, division of the alveolar ducts into alveolar …

We demonstrate that a primary source of elimination of inhaled macromolecules after
delivery to the lungs and before absorption into the systemic circulation owes to clearance …

Acute lung injury (ALI) or its aggravated stage acute respiratory distress syndrome (ARDS)
may lead to a life-threatening form of respiratory failure, resulting in high mortality of up to 30 …

Ambient ozone (O3) is a commonly encountered environmental air pollutant with
considerable impact on public health. Many other inhaled environmental toxicants can …

Background Some studies have demonstrated dexmedetomidine has anti-inflammatory
effect on septic rats. However, the mechanism of how dexmedetomidine exerts these effects …

Although phenotypically polarized macrophages are now generally classified into two major
subtypes termed proinflammatory M1 and anti-inflammatory M2 macrophages, a contributory …

Acute lung injury (ALI) is a severe health issue with significant morbidity and mortality.
Artemisinin is used for the treatment of fever and malaria in clinical practice …

Production of the proinflammatory cytokine tumor necrosis factor (TNF) must be precisely
regulated for effective host immunity without the induction of collateral tissue damage. Here …