Multiple contributing roles for NOS2 in LPS-induced acute airway inflammation in mice

T Okamoto, K Gohil, EI Finkelstein… - … of Physiology-Lung …, 2004 - journals.physiology.org
Acute lung inflammation and injury were induced by intranasal instillation of
lipopolysaccharide (LPS) in normal and type 2 nitric oxide synthase (NOS2)-deficient (NOS2 …

Sodium butyrate alleviates LPS-induced acute lung injury in mice via inhibiting HMGB1 release

N Li, X Liu, M Hong, X Huang, H Chen, J Xu… - International …, 2018 - Elsevier
Sodium butyrate (SB) is a short chain 4-carbon fatty acid salt naturally exists in animal fats.
Previous studies have proven that sodium butyrate has many beneficial functions such as …

Effects of macrophage inducible nitric oxide synthase in murine septic lung injury

KS Farley, LF Wang, HM Razavi… - … of Physiology-Lung …, 2006 - journals.physiology.org
Inducible nitric oxide synthase (iNOS) contributes importantly to septic pulmonary protein
leak in mice with septic acute lung injury (ALI). However, the role of alveolar macrophage …

Functional PU. 1 in macrophages has a pivotal role in NF-κB activation and neutrophilic lung inflammation during endotoxemia

M Karpurapu, X Wang, J Deng, H Park… - Blood, The Journal …, 2011 - ashpublications.org
Although the role of ETS family transcriptional factor PU. 1 is well established in
macrophage maturation, its role in mature macrophages with reference to sepsis-related …

[HTML][HTML] In vivo imaging of lung inflammation with neutrophil-specific 68Ga nano-radiotracer

J Pellico, AV Lechuga-Vieco, E Almarza, A Hidalgo… - Scientific Reports, 2017 - nature.com
In vivo detection and quantification of inflammation is a major goal in molecular imaging.
Furthermore, cell-specific detection of inflammation would be a tremendous advantage in …

Identification and characterization of alveolar and recruited lung macrophages during acute lung inflammation

W Han, H Tanjore, Y Liu, RP Hunt, SS Gutor… - The Journal of …, 2023 - journals.aai.org
To precisely identify mouse resident alveolar macrophages (AMs) and bone marrow (BM)–
derived macrophages, we developed a technique to separately label AMs and BM-derived …

TLR4 signaling attenuates ongoing allergic inflammation

JW Hollingsworth, GS Whitehead, KL Lin… - The Journal of …, 2006 - journals.aai.org
The relationship between LPS exposure and allergic asthma is poorly understood.
Epidemiologic studies in humans have found that exposure to LPS can protect, have no …

Inhaled lipid nanocarriers for pulmonary delivery of glucocorticoids: Previous strategies, recent advances and key factors description

MJ Altube, N Perez, EL Romero, MJ Morilla… - International Journal of …, 2023 - Elsevier
In view of the strong anti-inflammatory activity of glucocorticoids (GC) they are used in the
treatment of almost all inflammatory lung diseases. In particular, inhaled GC (IGC) allow high …

Induced hypothermia as a new approach to lung rest for the acutely injured lung

SB Hong, Y Koh, IC Lee, MJ Kim, WS Kim… - Critical Care …, 2005 - journals.lww.com
Objective: To investigate whether low-frequency ventilation during hypothermia could
attenuate lung injury associated with endotoxin and mechanical ventilation. Design …

Fraxin ameliorates lipopolysaccharide-induced acute lung injury in mice by inhibiting the NF-κB and NLRP3 signalling pathways

W Li, W Li, L Zang, F Liu, Q Yao, J Zhao, W Zhi… - International …, 2019 - Elsevier
Fraxin, the effective component of the Chinese traditional medicine Cortex Fraxini, is
reported to have anti-inflammatory effects. This study assessed the anti-inflammatory effect …